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Alimentary Pharmacology & Therapeutics
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7.73
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9643
Papers 9899
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#1Yao-Chun Hsu (ISU: I-Shou University)
#2Yen-Tsung Huang (AS: Academia Sinica)H-Index: 19
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#1Melek Simsek (VU: VU University Amsterdam)H-Index: 4
#2Nanne K. H. de Boer (VU: VU University Amsterdam)H-Index: 9
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1 CitationsSource
#1Shirley Sonmez (QMUL: Queen Mary University of London)
Last. Philip Woodland (QMUL: Queen Mary University of London)H-Index: 9
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BACKGROUND We have previously shown, ex vivo, that alginate solutions can have a topical protective effect on oesophageal mucosal biopsies exposed to simulated gastric juice. Oesophageal mucosal impedance can measure the duration of mucosal adherence of ionic solutions since the impedance drops when the solution is present, and rises to baseline as the solution clears. AIM To investigate the in vivo duration of adhesion of swallowed alginate solution to distal oesophageal mucosa. METHODS We stud...
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#1Hyunwoo Oh (Inje University)
#2Dae Won Jun (Hanyang University)H-Index: 21
Last. Mindie H. Nguyen (Stanford University)H-Index: 34
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BACKGROUND It is controversial whether chronic hepatitis B (CHB) patients have more non-liver comorbidities than non-CHB subjects. AIM To characterise the demographics, comorbidity and health utilisation of CHB patients in South Korea and compare them to matched controls. METHODS Using the Health Insurance Review & Assessment Service (HIRA) 2007-2016 database, adult patients with claims for CHB analysed. CHB cases and non-CHB controls matched in a 1:4 ratio using propensity score matching method...
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#1Bharati Kochar (Harvard University)H-Index: 6
#2Winston Cai (Harvard University)H-Index: 1
Last. Ashwin N. Ananthakrishnan (Harvard University)H-Index: 52
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BACKGROUND The prevalence of older adults with inflammatory bowel diseases (IBD) is increasing. Frailty is an important predictor of outcomes in many chronic disease states. The implications of frailty have not been well-delineated in IBD. AIMS To report the prevalence of a frailty-associated diagnosis and determine the association between frailty and mortality in a cohort of IBD patients. METHODS In a cohort of 11 001 IBD patients, we applied a validated definition of frailty using Internationa...
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BACKGROUND Fibrogenesis and inflammation contribute to the progression of cirrhosis. However, it is unknown if these processes also contribute to the development of cirrhotic cardiomyopathy (CCM). Novel magnetic resonance imaging with quantification of the extracellular volume (ECV) provides an estimate of the fibrotic remodelling in the liver and heart. AIM To investigate the relationship between liver and cardiac ECV in cirrhosis and their association with collagen turnover and inflammation. M...
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#1Anne K. Thomann (Heidelberg University)H-Index: 6
#2Joyce Wing Yan Mak (CUHK: The Chinese University of Hong Kong)H-Index: 2
Last. Siew C. Ng (CUHK: The Chinese University of Hong Kong)H-Index: 50
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BACKGROUND Psychiatric co-morbidities including depression and anxiety are common in inflammatory bowel diseases (IBD). Emerging evidence suggests that interactions between the gut microbiota and brain may play a role in the pathogenesis of psychiatric symptoms in IBD. AIM To review the literature on microbiota-brain-gut interactions in gut inflammation, psychosocial stress and mental disorders and to discuss the putative mediating role of gut microbiota in the development of psychiatric symptom...
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BACKGROUND Crohn's disease (CD) and hidradenitis suppurativa (HS), a chronic inflammatory skin disease, induce similar inflammatory lesions of the groin and gluteal area. Both diseases are characterised by an inadequate immune response to commensal bacteria in genetically predisposed subjects and can be associated. AIM To assess whether HS was associated with clinical and prognostic factors in CD. METHODS A retrospective case-control study included 4645 patients with CD referred to Saint-Antoine...
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#1Kumada TakashiH-Index: 42
#2Toyoda HidenoriH-Index: 42
Last. Philip J. Johnson (University of Liverpool)H-Index: 81
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BACKGROUND We conducted a prospective study using gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging (Gd-EOB-MRI) to determine whether sustained virological response (SVR) by direct-acting anti-viral (DAA) drugs suppresses hepatocarcinogenesis in patients with hepatitis C virus (HCV) infection. AIM To use serial Gd-EOB-MRI to assess the impact of DAAs on hepatocarcinogenesis. METHODS Between February 2008 and December 2018, 1083 consecutive patients w...
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