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Pathology Research International
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245
Papers 244
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Primary eosinophilic gastroenteritis and colitis (EGE) is a rare entity with unspecific clinical and endoscopic findings. Validated histopathologic criteria for confirming the diagnosis are lacking, because numeric values for normal or elevated concentrations of eosinophils in mucosal biopsies are varying between observers. To quantify this interobserver variance, we had the same set of 30 slides of eosinophilic-rich mucosal biopsies from the ileum and colon systematically reviewed by a panel of...
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#1Punyanuch Jindatanmanusan (Phramongkutklao College of Medicine)H-Index: 1
#2Sivat LuanraksaH-Index: 1
Last.Pasra Arnutti (Phramongkutklao College of Medicine)H-Index: 6
view all 5 authors...
Background and Objective. Evidence for the roles of matrix metalloproteinases-9 (MMP-9) in the healing process of diabetic foot ulcers has remained unclear. We therefore aimed to demonstrate the relationship of MMP-9 with the wound healing process and determine its potential usefulness in predicting the wound healing outcome. Methods. Twenty-two patients with diabetic foot ulcer were recruited. The wound size was determined, and the wound fluid was collected for the measurement of MMP-9 levels u...
3 CitationsSource
#1Shahid Pervez (Aga Khan University Hospital)H-Index: 20
#2Sidra Arshad (Aga Khan University Hospital)
Last.Brooj Abro (Aga Khan University Hospital)H-Index: 1
view all 3 authors...
Aim. Antigenic expression in epithelial cells can be heterogeneous which may pose a problem in immunohistochemical (IHC) analysis of tumor markers, in particular, predictive markers like HER2. Studies have shown that epithelial cells have distinct apical and basolateral domains which are separated by tight junctions. The cell membrane in these two domains has a different composition of macromolecules and hence can have variable antigen expression on immunohistochemistry. In our study, we aimed t...
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#1Rune Bjørneklett (University of Bergen)H-Index: 8
#2Vilde Solbakken (University of Bergen)H-Index: 1
Last.Anne-Siri FismenH-Index: 1
view all 4 authors...
Background. Classification of patients with anti-neutrophil cytoplasmic antibody-associated glomerulonephritis (ANCA-GN) into histological classes is useful for predicting a patient’s risk of progression to end-stage renal disease (ESRD). However, even in the worst prognostic group, the 5-year end-stage renal disease-free survival rate is as high as 50%. Objectives. To investigate those prognostic factors indicative of progression to ESRD in patients with ANCA-GN and sclerosing histology. Method...
1 CitationsSource
#1Hasrayati Agustina (UNPAD: Padjadjaran University)H-Index: 2
#2Ita Asyifa (UNPAD: Padjadjaran University)H-Index: 1
Last.Bethy S. Hernowo (UNPAD: Padjadjaran University)H-Index: 2
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Background. The diagnosis of Osteosarcoma (OSA) is not always straightforward. OSA may resemble Other Primary Bone Tumours (OPBT). The diagnosis of osteosarcoma is sometimes difficult especially in a very small specimen. Immunohistochemistry is one of ancillary testing types that can help the diagnosis of many tumours. The aim of this study was to evaluate the validity of Osteocalcin (OCN) and Alkaline Phosphatase (ALP) immunohistochemistry in discriminating OSA from OPBT. Method. This study inc...
2 CitationsSource
#1Nasim Taghavi (Shahid Beheshti University of Medical Sciences and Health Services)H-Index: 6
#2Zhaleh Mohsenifar (Shahid Beheshti University of Medical Sciences and Health Services)H-Index: 9
Last.Alireza Arjomandkhah (Shahid Beheshti University of Medical Sciences and Health Services)H-Index: 1
view all 4 authors...
3 CitationsSource
#1Tamara C. M. Lopes (UFOP: Universidade Federal de Ouro Preto)H-Index: 1
#2Débora Faria Silva (UFOP: Universidade Federal de Ouro Preto)H-Index: 1
Last.Simone Aparecida Rezende (UFOP: Universidade Federal de Ouro Preto)H-Index: 12
view all 8 authors...
Tartar emetic (TE) was the first drug used to treat leishmaniasis. However, its use was discontinued due to high toxicity. Association of TE with liposomes is a strategy to reduce its side effects. Pegylated liposomes (Lpeg) present lower rates of uptake by macrophages and prolonged circulation compared to their nonpegylated counterparts. However, repeated administration of Lpeg can cause an Accelerated Blood Clearance (ABC) phenomenon, whereby recognition of liposomes by antibodies results in f...
3 CitationsSource
#1Manoj Hang Limbu (SEU: Southeast University)H-Index: 1
#2Liu Lei (SEU: Southeast University)
Last.Chen Ping-sheng (SEU: Southeast University)
view all 6 authors...
It is already a proven fact that there exists a relationship between CLD (chronic liver disease) and kidney disease but still there is no available combined animal model of liver and kidney fibrosis on the same animal. An animal model is one of the important research tools in the field of medical science because it is important to build a model that can simulate the disease condition so that the particular disease can be studied. Therefore, the aim of this study is to build a less expensive, les...
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#1John Mokua Mose (JKUAT: Jomo Kenyatta University of Agriculture and Technology)H-Index: 2
#2David Muchina Kamau (JKUAT: Jomo Kenyatta University of Agriculture and Technology)H-Index: 2
Last.Simon Karanja (JKUAT: Jomo Kenyatta University of Agriculture and Technology)H-Index: 7
view all 7 authors...
Animal models for the toxoplasmosis are scarce and have limitations. In this study, a neurological mouse model was developed in BALB/c mice infected intraperitoneally with 15 cysts of a Toxoplasma gondii isolate. The mice were monitored for 42 days and euthanized at different time points. Another group of mice were orally treated with dexamethasone (DXM: 2.66 mg/kg daily, 5.32 mg/kg daily) at 42 days after infection and monitored for a further 42 days. A mortality rate of 15% and 28.6% was obser...
2 CitationsSource
#1Adeeb Salah (Kyoto University)H-Index: 3
#2Hajime Yoshifuji (Kyoto University)H-Index: 21
Last.Aya Miyagawa-Hayashino (Kyoto University)H-Index: 18
view all 10 authors...
Objectives. Immunoglobulin G4-related disease (IgG4-RD) is a multiorgan condition manifesting itself in different forms. This study aimed to investigate protein expression profiles and to find the possible biomarker for IgG4-RD by liquid chromatography mass spectrometry (LC-MS) using tissue sections in IgG4-RD patients. Methods. Protein expression profiles in five IgG4-related pancreatitis and three normal pancreatic samples were compared using LC-MS and were validated by quantitative real-time ...
5 CitationsSource
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