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Pathology Research International
Papers 245
1 page of 25 pages (245 results)
Primary eosinophilic gastroenteritis and colitis (EGE) is a rare entity with unspecific clinical and endoscopic findings. Validated histopathologic criteria for confirming the diagnosis are lacking, because numeric values for normal or elevated concentrations of eosinophils in mucosal biopsies are varying between observers. To quantify this interobserver variance, we had the same set of 30 slides of eosinophilic-rich mucosal biopsies from the ileum and colon systematically reviewed by a panel of...
Published on Oct 16, 2018in Pathology Research International
Punyanuch Jindatanmanusan (Phramongkutklao College of Medicine), Sivat Luanraksa + 2 AuthorsPasra Arnutti5
Estimated H-index: 5
(Phramongkutklao College of Medicine)
Background and Objective. Evidence for the roles of matrix metalloproteinases-9 (MMP-9) in the healing process of diabetic foot ulcers has remained unclear. We therefore aimed to demonstrate the relationship of MMP-9 with the wound healing process and determine its potential usefulness in predicting the wound healing outcome. Methods. Twenty-two patients with diabetic foot ulcer were recruited. The wound size was determined, and the wound fluid was collected for the measurement of MMP-9 levels u...
Published on Jul 24, 2018in Pathology Research International
Shahid Pervez19
Estimated H-index: 19
(Aga Khan University Hospital),
Sidra Arshad (Aga Khan University Hospital), Brooj Abro1
Estimated H-index: 1
(Aga Khan University Hospital)
Aim. Antigenic expression in epithelial cells can be heterogeneous which may pose a problem in immunohistochemical (IHC) analysis of tumor markers, in particular, predictive markers like HER2. Studies have shown that epithelial cells have distinct apical and basolateral domains which are separated by tight junctions. The cell membrane in these two domains has a different composition of macromolecules and hence can have variable antigen expression on immunohistochemistry. In our study, we aimed t...
Published on Jun 3, 2018in Pathology Research International
Rune Bjørneklett8
Estimated H-index: 8
(University of Bergen),
Vilde Solbakken1
Estimated H-index: 1
(University of Bergen)
+ 1 AuthorsAnne-Siri Fismen1
Estimated H-index: 1
Background. Classification of patients with anti-neutrophil cytoplasmic antibody-associated glomerulonephritis (ANCA-GN) into histological classes is useful for predicting a patient’s risk of progression to end-stage renal disease (ESRD). However, even in the worst prognostic group, the 5-year end-stage renal disease-free survival rate is as high as 50%. Objectives. To investigate those prognostic factors indicative of progression to ESRD in patients with ANCA-GN and sclerosing histology. Method...
Published on May 3, 2018in Pathology Research International
Hasrayati Agustina1
Estimated H-index: 1
(UNPAD: Padjadjaran University),
Ita Asyifa1
Estimated H-index: 1
(UNPAD: Padjadjaran University)
+ 1 AuthorsBethy S. Hernowo4
Estimated H-index: 4
(UNPAD: Padjadjaran University)
Background. The diagnosis of Osteosarcoma (OSA) is not always straightforward. OSA may resemble Other Primary Bone Tumours (OPBT). The diagnosis of osteosarcoma is sometimes difficult especially in a very small specimen. Immunohistochemistry is one of ancillary testing types that can help the diagnosis of many tumours. The aim of this study was to evaluate the validity of Osteocalcin (OCN) and Alkaline Phosphatase (ALP) immunohistochemistry in discriminating OSA from OPBT. Method. This study inc...
Published on Apr 4, 2018in Pathology Research International
Nasim Taghavi6
Estimated H-index: 6
(Shahid Beheshti University of Medical Sciences and Health Services),
Zhaleh Mohsenifar9
Estimated H-index: 9
(Shahid Beheshti University of Medical Sciences and Health Services)
+ 1 AuthorsAlireza Arjomandkhah1
Estimated H-index: 1
(Shahid Beheshti University of Medical Sciences and Health Services)
Published on Jan 16, 2018in Pathology Research International
Tamara C. M. Lopes1
Estimated H-index: 1
(UFOP: Universidade Federal de Ouro Preto),
Débora Faria Silva1
Estimated H-index: 1
(UFOP: Universidade Federal de Ouro Preto)
+ 5 AuthorsSimone Aparecida Rezende12
Estimated H-index: 12
(UFOP: Universidade Federal de Ouro Preto)
Tartar emetic (TE) was the first drug used to treat leishmaniasis. However, its use was discontinued due to high toxicity. Association of TE with liposomes is a strategy to reduce its side effects. Pegylated liposomes (Lpeg) present lower rates of uptake by macrophages and prolonged circulation compared to their nonpegylated counterparts. However, repeated administration of Lpeg can cause an Accelerated Blood Clearance (ABC) phenomenon, whereby recognition of liposomes by antibodies results in f...
Published on Sep 18, 2017in Pathology Research International
Daniel Zaccarini2
Estimated H-index: 2
(State University of New York Upstate Medical University),
Kamal K. Khurana20
Estimated H-index: 20
(State University of New York Upstate Medical University)
Objective. Anal cytology is being increasingly used as part of anal cancer screening in patients at high risk for anal neoplasia. Most studies in anal cytology have focused on correlating the abnormal anal Pap smear with histopathologic outcomes. The aim of this study was to document histopathologic or repeat anal cytology outcomes in patients with unsatisfactory cytology. Materials and Methods. Unsatisfactory anal Pap tests in high risk male patients were correlated with follow-up histopatholog...
Published on Aug 1, 2017in Pathology Research International
Manoj Hang Limbu1
Estimated H-index: 1
(SEU: Southeast University),
Liu Lei (SEU: Southeast University)+ 3 AuthorsChen Ping-sheng (SEU: Southeast University)
It is already a proven fact that there exists a relationship between CLD (chronic liver disease) and kidney disease but still there is no available combined animal model of liver and kidney fibrosis on the same animal. An animal model is one of the important research tools in the field of medical science because it is important to build a model that can simulate the disease condition so that the particular disease can be studied. Therefore, the aim of this study is to build a less expensive, les...
Published on May 24, 2017in Pathology Research International
John Mokua Mose1
Estimated H-index: 1
(JKUAT: Jomo Kenyatta University of Agriculture and Technology),
David Muchina Kamau2
Estimated H-index: 2
(JKUAT: Jomo Kenyatta University of Agriculture and Technology)
+ 4 AuthorsSimon Karanja7
Estimated H-index: 7
(JKUAT: Jomo Kenyatta University of Agriculture and Technology)
Animal models for the toxoplasmosis are scarce and have limitations. In this study, a neurological mouse model was developed in BALB/c mice infected intraperitoneally with 15 cysts of a Toxoplasma gondii isolate. The mice were monitored for 42 days and euthanized at different time points. Another group of mice were orally treated with dexamethasone (DXM: 2.66 mg/kg daily, 5.32 mg/kg daily) at 42 days after infection and monitored for a further 42 days. A mortality rate of 15% and 28.6% was obser...