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Radiotherapy and Oncology
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#1Yasir AlayedH-Index: 2
#2Harvey QuonH-Index: 10
Last. Geordi PangH-Index: 15
view all 18 authors...
Abstract Background Prostate stereotactic ablative radiotherapy (SABR) regimens differ in time, dose, and fractionation. We report an update of a multicentre, Canadian randomized phase II study to investigate the impact of overall treatment time on quality of life (QOL), efficacy, and toxicity. Methods Men with intermediate risk prostate cancer were randomized to 40 Gy in 5 fractions delivered every other day (EOD) versus once per week (QW). Primary outcome was proportion of patients experiencin...
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#1Alexander Grimwood (ICR: Institute of Cancer Research)H-Index: 2
#2Hassan Rivaz (Concordia University)H-Index: 15
Last. Emma J. Harris (ICR: Institute of Cancer Research)H-Index: 17
view all 8 authors...
BACKGROUND AND PURPOSE: Daily image guidance is standard care for prostate radiotherapy. Innovations which improve the accuracy and efficiency of ultrasound guidance are needed, particularly with respect to reducing interobserver variation. This study explores automation tools for this purpose, demonstrated on the Elekta Clarity Autoscan(R). The study was conducted as part of the Clarity Pro trial (NCT02388308). MATERIALS AND METHODS: Ultrasound scan volumes were collected from 32 patients. Pros...
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#1Ying Song (Sichuan University)H-Index: 1
#2Junjie Hu (Sichuan University)
Last. Zhang Yi (Sichuan University)
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Abstract Purpose To apply a deep neural network to predict dose distributions of rectal cancer patients for accelerated volume modulated arc technique (VMAT) planning. Materials and methods Computed tomography scans and approved VMAT plans together with Doseapproved of 187 patients treated from February 2018 to April 2019 were randomly selected for this retrospective study. The deep neural network DeepLabv3+ was applied for dose distribution prediction. A prior dose information-aided planning sc...
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#1Anne W.M. Lee (HKU: University of Hong Kong)H-Index: 35
#2Zhi-Yuan Xu (HKU: University of Hong Kong)
Last. Jacob Kai Ki Cheung (HKU: University of Hong Kong)H-Index: 1
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The COVID-19 pandemic is a devastating catastrophe to the whole world, China is the first country seriously affected. This review shows that it is possible to stop wide-spread infection in the country and to provide good quality oncology services even during this challenging period, through concerted efforts with well-organized actions at all levels (National/Municipal, Hospital and Department). The key strategies leading to successful impacts are summarized for sharing. In addition to making pr...
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#1Patries M. Herst (University of Otago)H-Index: 17
Last. Shaun A. CostelloH-Index: 1
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Abstract Purpose Acute radiation cystitis affects the quality of life of many prostate cancer patients. A previous pilot study suggested that cranberry capsules may decrease some of the symptoms of acute radiation cystitis. Here we further test their effectiveness in a multicentre double blinded placebo-controlled clinical trial. Material and Methods A total of 108 prostate cancer patients were recruited at three New Zealand hospitals between September 2016 and January 2019. Out of this cohort, ...
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Abstract We analyzed 135 patients (including 27 EGFR-mutant and 29 EGFR-wild) with T1-3N0M0 non-squamous NSCLC treated by PBT. Considering the 3-year cumulative incidence, the EGFR-mutant group showed a significantly lower infield failure rate (9% vs 27%, p=0.02) and higher out-of-field failure rate (67% vs 40%, p=0.02) than the EGFR-wild group.
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PURPOSE: To develop and evaluate a fast, automated multi-criterial treatment planning approach for adaptive high-dose-rate (HDR) intracavitary + interstitial brachytherapy (BT) for locally advanced cervical cancer. METHODS AND MATERIALS: Twenty-two previously delivered single fraction MRI-based HDR treatment plans (SFclin) were used to guide training of our in-house system for multi-criterial autoplanning, aiming for an autoplan quality superior to the training plans, while respecting the clinic...
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#1S. Yoon (UCLA: University of California, Los Angeles)
Last. A.U. KishanH-Index: 1
view all 9 authors...
PURPOSE: Stereotactic body radiotherapy (SBRT) in the post-prostatectomy setting is investigational. A major concern is the deformable prostate bed clinical target volume (CTV) and the closely juxtaposed organs-at-risk (OARs). We report a volumetric and dosimetric analysis of kilovoltage cone-beam CT (CBCT) data from the first 18 patients enrolled on a phase II trial of post-prostatectomy SBRT. With instructions on bladder filling and rectal preparation, we hypothesized acceptable CTV coverage w...
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#1Ronald ChowH-Index: 10
#2Peter Hoskin (University of Manchester)H-Index: 66
Last. Henry Lam (Sunnybrook Health Sciences Centre)H-Index: 12
view all 12 authors...
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#1Christian FiandraH-Index: 13
#2L. Rossi (EUR: Erasmus University Rotterdam)H-Index: 2
Last. E. GinoH-Index: 1
view all 28 authors...
Abstract Purpose The first clinical genetic autoplanning algorithm (Genetic Planning Solution, GPS) was validated in ten radiotherapy centres for prostate cancer VMAT by comparison with manual planning (Manual). Methods Although there were large differences among centres in planning protocol, GPS was tuned with the data of a single centre and then applied everywhere without any centre-specific fine-tuning. For each centre, ten Manual plans were compared with autoGPS plans, considering dosimetric...
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Medical physics
Brachytherapy
Nuclear medicine
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