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Journal of Neuroimmunology
Papers 10573
1 page of 1,058 pages (10.6k results)
Published in Journal of Neuroimmunology 2.83
André Caetano4
Estimated H-index: 4
(NOVA: Universidade Nova de Lisboa),
Filipa Ladeira3
Estimated H-index: 3
+ -3 AuthorsElmira Medeiros (NOVA: Universidade Nova de Lisboa)
Abstract A 26-year-old female presented with acute onset distal paraparesis, upper limb tremor and bilateral facial palsy. Neurophysiology revealed a sensorimotor demyelinating polyneuropathy and lumbar puncture revealed an albuminocytologic dissociation. Neuroaxis MRI revealed bilateral facial nerve and cauda equina enhancement. Initially diagnosed as Guillain-Barre Syndrome, poor response to intravenous immunoglobulin, persistent deterioration, anti-neurofascin-155 antibodies and clinical resp...
Published in Journal of Neuroimmunology 2.83
Pia M. Vidal1
Estimated H-index: 1
(UHN: University Health Network),
Antigona Ulndreaj4
Estimated H-index: 4
(U of T: University of Toronto)
+ -3 AuthorsMichael G. Fehlings93
Estimated H-index: 93
(U of T: University of Toronto)
Abstract Background Degenerative cervical myelopathy (DCM) is the most common cause of non-traumatic spinal cord injury worldwide. Surgical decompression is recommended as the preferred treatment strategy for DCM as it halts disease progression and improves neurologic symptoms. We previously demonstrated that neuroinflammation, including monocytes, plays a critical role in the pathobiology of DCM and in ischemic-reperfusion injury (IRI) following surgical decompression. Monocytes are able to ent...
Published in Journal of Neuroimmunology 2.83
Jingfang Lin (Sichuan University), Linmao Zheng (Sichuan University)+ -3 AuthorsZhen Hong (Sichuan University)
Abstract IgG4-related disease (IgG4-RD) is an immune-mediated condition that affects multiple organ systems with tumorlike swelling. Here, for the first time, we report a rare case of IgG4-RD that involves the cerebral parenchyma, intramedullary spinal cord and lymph nodes. The diagnosis of IgG4-RD was made based on histological features, multi organ involvement and high serum IgG4 levels. The patient responded well to glucocorticoid treatment. Our case broadens the phenotypic presentation for t...
Published in Journal of Neuroimmunology 2.83
Pabitra Basnyat3
Estimated H-index: 3
(UTA: University of Tampere),
Marja-Liisa Sumelahti15
Estimated H-index: 15
(UTA: University of Tampere)
+ -3 AuthorsSanna Hagman6
Estimated H-index: 6
(UTA: University of Tampere)
Abstract TL1A/DR3/DcR3 pathway is an important mediator of inflammatory responses and contributes to the pathogenesis of several chronic inflammatory diseases. Therefore, we analysed PBMC gene expression of these molecules in 30 relapsing-remitting multiple sclerosis (RRMS) patients, 8 secondary progressive MS (SPMS), 9 primary progressive MS (PPMS), 11 clinically isolated syndrome (CIS) patients, and 16 healthy controls (HCs), to evaluate their biomarker potential in MS. The results showed sign...
Published in Journal of Neuroimmunology 2.83
Ali A. Weinstein15
Estimated H-index: 15
(Inova Health System),
J. Michael Estep3
Estimated H-index: 3
(Inova Health System)
+ -3 AuthorsLynn H. Gerber46
Estimated H-index: 46
(Inova Health System)
Abstract An important extrahepatic consequence of Hepatitis C is its adverse impact on the central nervous system and cognitive performance. We aimed to determine whether there is a significant relationship between selected neurotransmitters and cytokines and cognitive performance in patients with Chronic Hepatitis C before and after achieving sustained virologic response (SVR). Pre-SVR, elevated kynurenine was associated with increased immediate and delayed visual memory, whereas post-SVR the p...
Published on Jul 18, 2019in Journal of Neuroimmunology 2.83
Margherita Nosadini10
Estimated H-index: 10
Irene Toldo17
Estimated H-index: 17
+ 5 AuthorsStefano Sartori20
Estimated H-index: 20
Abstract Leucine-rich glioma-inactivated protein 1 (LGI1) and contactin-associated protein-like 2 (CASPR2) neurological autoimmunity in adults has been associated with various clinical syndromes involving central, peripheral and autonomic nervous system, while data in children is limited. We perform the first systematic literature review on paediatric LGI1 and CASPR2 autoimmunity, with focus on clinical data, in order to contribute to the definition of clinical features of LGI1 and CASPR2 autoim...
Published on Oct 1, 2019in Journal of Neuroimmunology 2.83
Jennifer M. Loftis22
Estimated H-index: 22
(OHSU: Oregon Health & Science University),
Jonathan Taylor1
Estimated H-index: 1
(OHSU: Oregon Health & Science University)
+ 1 AuthorsEvan J. Firsick
Abstract Viruses that invade the central nervous system (CNS) can cause neuropsychiatric impairments. Similarly, chronic alcohol exposure can induce inflammatory responses that alter brain function. However, the effects of a chronic viral infection and comorbid alcohol use on neuroinflammation and behavior are not well-defined. We investigated the role of heavy alcohol intake in regulating inflammatory responses and behavioral signs of cognitive impairments in mice infected with lymphocytic chor...
Published on Jul 1, 2019in Journal of Neuroimmunology 2.83
Abstract Background Some previous studies already explored associations of interleukin-6 ( IL-6 ) and interleukin-10 ( IL-10 ) polymorphisms with ischemic stroke (IS). However, the results were conflicting. In this meta-analysis, we aimed to better analyze the relationship between IL-6/IL-10 polymorphisms and IS in a larger pooled population. Methods We performed a systematic search of PubMed, Web of Science, Embase and CNKI. We calculated pooled odds ratios (ORs) and 95% confidence intervals (C...
Published in Journal of Neuroimmunology 2.83
Christine Miaskowski70
Estimated H-index: 70
(UCSF: University of California, San Francisco),
Kimberly Topp23
Estimated H-index: 23
(UCSF: University of California, San Francisco)
+ -3 AuthorsKord M. Kober17
Estimated H-index: 17
(UCSF: University of California, San Francisco)
Abstract Paclitaxel is a common chemotherapy drug associated with the development of chronic paclitaxel-induced peripheral neuropathy (PIPN). PIPN is associated with neuroinflammatory mechanisms in pre-clinical studies. Here, we evaluated for differential gene expression (DGE) in peripheral blood between breast cancer survivors with and without PIPN and for neuroinflammatory (NI) related signaling pathways and whole-transcriptome profiles from other experiments. Pathway impact analysis identifie...