OBJECTIVE: To provide guidance for the management of gout, including indications for and optimal use of urate-lowering therapy (ULT), treatment of gout flares, and lifestyle and other medication recommendations. METHODS: Fifty-seven population, intervention, comparator, and outcomes questions were developed, followed by a systematic literature review, including network meta-analyses with ratings of the available evidence according to the Grading of Recommendations Assessment, Development and Eva...
Last. Jonathan S. Hausmann(BIDMC: Beth Israel Deaconess Medical Center)H-Index: 9
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The coronavirus disease 2019 (COVID-19) Global Rheumatology Alliance (C19-GRA) was formed in March 2020 as a grassroots organization to coordinate the response of the international rheumatology community to the pandemic [1]. The C19-GRA launched an international, secure, de-identified physician registry of patients with rheumatic diseases infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to provide insights into the management and treatment of COVID-19 in this popula...
A report by Mosor et al. (1) exemplifies an interesting academic exercise toward a laudable goal, but the issue of initiating treatment in asymptomatic individuals really seems a moot issue. Until there are sufficient appointments (given limited access to rheumatologists) for treatment of individuals who actually have documented disease, how can one justify delaying their appointments - behind that of healthy individuals who it is speculated might develop a problem at some time in the future?
INTRODUCTION: Despite randomized controlled trials showing relatively comparable clinical outcomes with triple therapy (Triple; MTX, SSZ, HCQ) vs combination therapy with TNFi+MTX (TNF/MTX), the real-world experience comparing these strategies has not been well studied. METHODS: We evaluated discontinuation and clinical effectiveness of Triple vs TNFi/MTX therapy amongst RA patients in the Corrona registry. Propensity score matching (up to 1:3) was used to adjust for imbalances, with stratificat...
OBJECTIVE: To explore the sexual and reproductive health (SRH) care and counseling needs of young women with rheumatic diseases in the context of their rheumatology care. METHODS: Semi-structured qualitative telephone interviews were conducted with female patients with rheumatic diseases aged 18-45 years (N=30). Women were recruited from outpatient rheumatology clinics in western Pennsylvania. Interviews were audio-recorded and transcribed verbatim. A codebook was inductively developed based on ...
Last. Andrew Stokes(BU: Boston University)H-Index: 18
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OBJECTIVE: To examine the association between weight change from young adulthood to midlife and risk of incident arthritis. METHODS: Using data from the National Health and Nutrition Examination Survey (NHANES), we categorized participants into weight change categories based on their recalled weight during young adulthood and midlife. We estimated the association of weight change and developing an arthritis condition over 10 years using adjusted Cox models. Findings were extrapolated to the US p...
#1Tate M. Johnson(UNMC: University of Nebraska Medical Center)
#2James Robert O'Dell(UNMC: University of Nebraska Medical Center)H-Index: 40
Last. Bryant R. England(UNMC: University of Nebraska Medical Center)H-Index: 7
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We thank Dr. Masi for his interest in our systematic review and meta-analysis of the Multi-Biomarker Disease Activity (MBDA) score in rheumatoid arthritis (RA) and for sharing his perspectives on the MBDA score. As noted by Dr. Masi, there have been few independent studies and cost-effectiveness analyses of the MBDA score in RA to date. We agree that these studies, and those evaluating psychometric properties such as construct validity, are needed to better determine the value of this test in ca...