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BMC Medicine
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#1Markos Klonizakis (SHU: Sheffield Hallam University)H-Index: 15
#2Anil GumberH-Index: 12
Last. Leonie S. BroseH-Index: 19
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#1Paola Cocco (University of Leeds)
Last. Bethany ShinkinsH-Index: 11
view all 5 authors...
BACKGROUND: A Target Product Profile (TPP) outlines the necessary characteristics of an innovative product to address an unmet clinical need. TPPs could be used to better guide manufacturers in the development of 'fit for purpose' tests, thus increasing the likelihood that novel tests will progress from bench to bedside. However, there is currently no guidance on how to produce a TPP specifically for medical tests. METHODS: A systematic review was conducted to summarise the methods currently use...
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#1Nida Ziauddeen (University of Southampton)H-Index: 4
#2Sam Wilding (University of Southampton)H-Index: 1
Last. Nisreen A. Alwan (University of Southampton)H-Index: 16
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BACKGROUND: Nearly a third of children in the UK are overweight, with the prevalence in the most deprived areas more than twice that in the least deprived. The aim was to develop a risk identification model for childhood overweight/obesity applied during pregnancy and early life using routinely collected population-level healthcare data. METHODS: A population-based anonymised linked cohort of maternal antenatal records (January 2003 to September 2013) and birth/early-life data for their children...
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#1James J. GilchristH-Index: 7
#2Sophie UyogaH-Index: 17
Last. Thomas N. WilliamsH-Index: 40
view all 10 authors...
#1Emma Sypes (U of C: University of Calgary)
#2Chloe de Grood (U of C: University of Calgary)H-Index: 2
Last. Henry T. Stelfox (AHS: Alberta Health Services)H-Index: 37
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BACKGROUND: Many decisions regarding health resource utilization flow through the patient-clinician interaction. Thus, it represents a place where de-implementation interventions may have considerable effect on reducing the use of clinical interventions that lack efficacy, have risks that outweigh benefits, or are not cost-effective (i.e., low-value care). The objective of this systematic review with meta-analysis was to determine the effect of de-implementation interventions that engage patient...
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#1Edoardo Aromataris (University of Adelaide)H-Index: 19
#2Cindy Stern (University of Adelaide)H-Index: 10
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#1Kevin M. TrentinoH-Index: 8
#2Shannon FarmerH-Index: 14
Last. Kevin MurrayH-Index: 21
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#1Christopher Jarvis (Lond: University of London)H-Index: 1
#2Kevin van Zandvoort (Lond: University of London)H-Index: 1
Last. W. John Edmunds (Lond: University of London)H-Index: 42
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BACKGROUND: To mitigate and slow the spread of COVID-19, many countries have adopted unprecedented physical distancing policies, including the UK. We evaluate whether these measures might be sufficient to control the epidemic by estimating their impact on the reproduction number (R0, the average number of secondary cases generated per case). METHODS: We asked a representative sample of UK adults about their contact patterns on the previous day. The questionnaire was conducted online via email re...
1 CitationsSource
#1Olga Perski (UCL: University College London)H-Index: 4
#2Emma Beard (UCL: University College London)H-Index: 18
Last. Jamie Brown (UCL: University College London)H-Index: 27
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BACKGROUND: There is a decreasing trend in the proportion of individuals who perceive e-cigarettes to be less harmful than conventional cigarettes across the UK, Europe and the US. It is important to assess whether this may influence the use of e-cigarettes. We aimed to estimate, using a time series approach, whether changes in harm perceptions among current tobacco smokers have been associated with changes in the prevalence of e-cigarette use in England, with and without stratification by age, ...
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