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Current Biology
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Published on Jan 6, 2019in bioRxiv
Christine M. Field35
Estimated H-index: 35
(Harvard University),
James Pelletier3
Estimated H-index: 3
(Harvard University),
Timothy J. Mitchison117
Estimated H-index: 117
(Harvard University)
We investigated how bulk cytoplasm prepares for cytokinesis in Xenopus laevis eggs, which are large, rapidly dividing cells. The egg midplane is demarcated by Chromosomal Passenger Complex (CPC) localized on microtubule bundles between asters. Using an extract system and intact eggs we found that local kinase activity of the AURKB subunit of the CPC caused disassembly of F-actin and keratin between asters, and local softening of the cytoplasm as assayed by flow patterns. Beads coated with active...
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Published on Nov 8, 2018in bioRxiv
Jack E Green (Centre national de la recherche scientifique), Matthieu Cavey3
Estimated H-index: 3
(Centre national de la recherche scientifique)
+ 2 AuthorsBenjamin Prud'homme13
Estimated H-index: 13
(Centre national de la recherche scientifique)
Morphological diversity is dominated by variation in body proportion. Yet the cellular processes underlying differential growth of morphological traits between species remain largely unknown. Here we compare the ovipositors of two closely related species, Drosophila melanogaster and D. suzukii. D. suzukii has switched its egg laying niche from rotting to ripe fruit. Along with this shift, the D. suzukii ovipositor has undergone a significant change in size and shape. Using an allometric approach...
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Published on May 5, 2018in bioRxiv
Adam M. P. Miller3
Estimated H-index: 3
(Cornell University),
William Mau2
Estimated H-index: 2
(Boston University),
David M. Smith16
Estimated H-index: 16
(Cornell University)
The retrosplenial cortex (RSC) is important for long-term contextual memory and spatial navigation, but little is known about how RSC neural representations develop with experience. We recorded neuronal activity in the RSC of rats as they learned a continuous spatial alternation task and found that the RSC slowly developed a population-level representation of the rat9s spatial location and current trajectory to the goal. After the rats reached peak performance, RSC firing patterns became predict...
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Published on Jun 1, 2019in Current Biology 9.25
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