Human Reproduction
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#2Mingru YinH-Index: 3
Last. Qianqian ZhuH-Index: 4
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STUDY QUESTION To evaluate the impact of storage time after vitrification on embryo viability, pregnancy outcomes and neonatal outcomes. SUMMARY ANSWER The prolonged storage time of vitrified embryos negatively affected pregnancy outcomes, including biochemical pregnancy rate, clinical pregnancy and live birth rate; but did not influence neonatal outcomes. WHAT IS KNOWN ALREADY Although vitrification has been the fundamental tool of ART treatments in recent years, few studies have explored the i...
#1Artur Ludwin (Jagiellonian University)H-Index: 13
#1Jigal Haas (Sheba Medical Center)H-Index: 13
#2Rawad BassilH-Index: 3
Last. Robert F. Casper (U of T: University of Toronto)H-Index: 64
view all 7 authors...
STUDY QUESTION Does co-administration of GnRH agonist and Human chorionic gonadotropin (hCG; dual trigger) in IVF cycles improve the number of mature oocytes and pregnancy outcome compared to hCG alone? SUMMARY ANSWER Using the dual trigger for final follicular maturation increases the number of oocytes, mature oocytes and number of blastocysts (total and top-quality) compared to triggering with hCG alone. WHAT IS KNOWN ALREADY hCG is used at the end of controlled ovarian hyperstimulation as a s...
#1Dongshan Zhu (UQ: University of Queensland)H-Index: 6
#2Hsin-Fang Chung (UQ: University of Queensland)H-Index: 9
Last. Graham G. Giles (Monash University)H-Index: 113
view all 16 authors...
Study question How does the risk of cardiovascular disease (CVD) vary with type and age of menopause? Summary answer Earlier surgical menopause (e.g. What is known already Earlier age at menopause has been linked to an increased risk of CVD mortality and all-cause mortality, but the extent that this risk of CVD varies by type of menopause and the role of postmenopausal HRT use in reducing this risk is unclear. Study design, size, duration Pooled individual-level data of 203 767 postmenopausal wo...
#1Stine A. Holmboe (UCPH: University of Copenhagen)H-Index: 8
#2Lærke Priskorn (UCPH: University of Copenhagen)H-Index: 9
Last. Niels Jørgensen (UCPH: University of Copenhagen)H-Index: 63
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STUDY QUESTION Are use of e-cigarettes and snuff associated with testicular function as previously shown for conventional cigarettes and marijuana? SUMMARY ANSWER Use of e-cigarettes is associated with reduced semen quality but not with higher serum testosterone level as observed for conventional cigarette use. Snuff use was not associated with markers of testicular function. WHAT IS KNOWN ALREADY Cigarette smoking has previously been associated with higher testosterone levels and impaired semen...
#1Soledad Henríquez (University of Chile)H-Index: 3
#2Paulina Kohen (University of Chile)H-Index: 18
Last. Luigi Devoto (University of Chile)H-Index: 29
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STUDY QUESTION Do alterations in pro- and anti-angiogenic estrogen metabolites in follicular fluid (FF) contribute to the follicular growth arrest and anovulation associated with polycystic ovary syndrome (PCOS)? SUMMARY ANSWER FF of PCOS women with anovulation have reduced levels of pro-angiogenic estrogen metabolites (EMs) and vascular endothelial growth factor (VEGF) compared to that of fertile women with regular menstrual cycles, but exogenous gonadotropins increase the pro-angiogenic EMs an...
#1S.J. Chua (University of Adelaide)
#2N. A. Danhof (UvA: University of Amsterdam)H-Index: 5
Last. Wayne R. Gillett (University of Otago)H-Index: 14
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#1Chiara Talia (Aberd.: University of Aberdeen)
Last. Paul A. Fowler (Aberd.: University of Aberdeen)H-Index: 36
view all 4 authors...
STUDY QUESTION Does having a male co-twin influence the female twin's reproductive outcomes? SUMMARY ANSWER Women with a male co-twin had the same chances of being pregnant and having children compared to same-sex twin pairs. WHAT IS KNOWN ALREADY According to the twin testosterone transfer (TTT) hypothesis, in an opposite-sex twin pregnancy, testosterone transfer from the male to the female co-twin occurs. A large body of literature supports the negative impact of prenatal testosterone exposure...
This opinion paper addresses the literature regarding repeated implantation failure (RIF) in IVF embryo transfer programmes. We provide several lines of discussion as to why such diagnosis might be wrong, why it should not be a call for action or a reason to change the course of treatment, and how RIF biases the quality of the publications and leads to the use of unnecessary and costly adjuvant procedures beyond basic IVF. We argue that these costly add-on procedures are being offered to patient...
#1Phillip A. Romanski (Cornell University)
#2Pietro Bortoletto (Cornell University)
Last. Glenn L. Schattman (Cornell University)H-Index: 19
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STUDY QUESTION Will a delay in initiating IVF treatment affect pregnancy outcomes in infertile women with diminished ovarian reserve? SUMMARY ANSWER A delay in IVF treatment up to 180 days does not affect the live birth rate for women with diminished ovarian reserve when compared to women who initiate IVF treatment within 90 days of presentation. WHAT IS KNOWN ALREADY In clinical practice, treatment delays can occur due to medical, logistical or financial reasons. Over a period of years, a gradu...
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