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Archives of General Psychiatry
Papers 9401
1 page of 941 pages (9,401 results)
Published on Jan 1, 2013in Archives of General Psychiatry
Daphne-Zacharenia Kounali10
Estimated H-index: 10
(UoB: University of Bristol),
Stanley Zammit47
Estimated H-index: 47
(UoB: University of Bristol)
+ 2 AuthorsNicola Wiles32
Estimated H-index: 32
Published on Dec 1, 2012in Archives of General Psychiatry
Carl Ernst27
Estimated H-index: 27
(Broad Institute),
Christian R. Marshall47
Estimated H-index: 47
(U of T: University of Toronto)
+ 26 AuthorsVamsee Pillalamarri12
Estimated H-index: 12
(U of O: University of Ottawa)
Context Brain-derived neurotrophic factor (BDNF) is suspected of being a causative factor in psychiatric disorders based on case reports or studies involving large structural anomalies. Objective To determine the involvement of BDNF in human psychopathology. Design Case-control study. Setting Microarray-based comparative genomic hybridization data from 7 molecular diagnostic centers including 38 550 affected subjects and 28 705 unaffected subjects. Patients Subjects referred to diagnostic screen...
16 Citations Source Cite
Published on Dec 1, 2012in Archives of General Psychiatry
Mette Ødegaard Nielsen7
Estimated H-index: 7
Egill Rostrup45
Estimated H-index: 45
+ 5 AuthorsBirte Glenthøj35
Estimated H-index: 35
Context Schizophrenic symptoms are linked to a dysfunction of dopamine neurotransmission and the brain reward system. However, it remains unclear whether antipsychotic treatment, which blocks dopamine transmission, improves, alters, or even worsens the reward-related abnormalities. Objective To investigate changes in reward-related brain activations in schizophrenia before and after antipsychotic monotherapy with a dopamine D 2 /D 3 antagonist. Design Longitudinal cohort study. Setting Psychiatr...
80 Citations Source Cite
Published on Dec 1, 2012in Archives of General Psychiatry
In Kyoon Lyoo9
Estimated H-index: 9
(Ewha Womans University),
Sujung Yoon15
Estimated H-index: 15
(Catholic University of Korea)
+ 11 AuthorsDajung J. Kim5
Estimated H-index: 5
(SNU: Seoul National University)
Context Neural substrates that may be responsible for the high prevalence of depression in type 1 diabetes mellitus (T1DM) have not yet been elucidated. Objective To investigate neuroanatomic correlates of depression in T1DM. Design Case-control study using high-resolution brain magnetic resonance images. Settings Joslin Diabetes Center and McLean Hospital, Massachusetts, and Seoul National University Hospital, South Korea. Participants A total of 125 patients with T1DM (44 subjects with ≥1 prev...
22 Citations Source Cite
Published on Dec 1, 2012in Archives of General Psychiatry
Theresa L. Osypuk25
Estimated H-index: 25
Tchetgen Tchetgen29
Estimated H-index: 29
(Harvard University)
+ 4 AuthorsM. Maria Glymour38
Estimated H-index: 38
(Harvard University)
Context Extensive observational evidence indicates that youth in high-poverty neighborhoods exhibit poor mental health, although not all children may be affected similarly. Objective To use experimental evidence to assess whether gender and family health problems modify the mental health effects of moving from high- to low-poverty neighborhoods. Design Randomized controlled trial. Setting Volunteer low-income families in public housing in 5 US cities between 1994-1997. Participants We analyze 4-...
51 Citations Source Cite
Published on Dec 1, 2012in Archives of General Psychiatry
Jose Mathews6
Estimated H-index: 6
John W. Newcomer52
Estimated H-index: 52
+ 5 AuthorsDeanna M75
Estimated H-index: 75
Context Iatrogenic obesity caused by atypical antipsychotics increases the rate of death from all causes. Olanzapine is a commonly prescribed atypical antipsychotic medication that frequently causes weight gain. To our knowledge, the neural correlates of this weight gain have not been adequately studied in humans. Objective To test the hypothesis that olanzapine treatment disrupts the neural activity associated with the anticipation and receipt (consumption) of food rewards (chocolate milk and t...
19 Citations Source Cite
Published on Dec 1, 2012in Archives of General Psychiatry
Ian Kelleher24
Estimated H-index: 24
Fionnuala Lynch9
Estimated H-index: 9
+ 4 AuthorsMary Cannon51
Estimated H-index: 51
Context Recent evidence from both clinical and population research has pointed to psychotic symptoms as potentially important markers of risk for suicidal behavior. However, to our knowledge, there have been no epidemiological studies to date that have reported data on psychotic symptoms and suicidality in individuals who have been clinically assessed for suicidal behavior. Objectives To explore associations between psychotic symptoms in nonpsychotic adolescents and risk for suicidal behavior in...
99 Citations Source Cite
Published on Dec 1, 2012in Archives of General Psychiatry
Michael F. Green88
Estimated H-index: 88
Gerhard Hellemann39
Estimated H-index: 39
+ 2 AuthorsJonathan K. Wynn28
Estimated H-index: 28
Context Schizophrenia remains a highly disabling disorder, but the specific determinants and pathways that lead to functional impairment are not well understood. It is not known whether these key determinants of outcome lie on 1 or multiple pathways. Objective To evaluate theoretically based models of pathways to functional outcome starting with early visual perception. The intervening variables were previously established determinants of outcome drawn from 2 general categories: ability (ie, soc...
194 Citations Source Cite
Published on Dec 1, 2012in Archives of General Psychiatry
Katherine M. Keyes51
Estimated H-index: 51
(Columbia University),
John E. Schulenberg66
Estimated H-index: 66
+ 4 AuthorsDeborah S. Hasin83
Estimated H-index: 83
(Columbia University)
Context The substantial changes in adolescent alcohol use prevalence over time suggest that population-level environmental factors are important determinants of use, yet the potential influence of such environmental factors is inadequately understood. Objective To investigate whether adolescents in birth cohorts and/or time periods characterized by restrictive social norms toward alcohol were at decreased risk for alcohol use and binge drinking, controlling for individual attitudes (disapproval)...
55 Citations Source Cite
Published on Dec 1, 2012in Archives of General Psychiatry
Laura A. Thomas10
Estimated H-index: 10
Melissa A. Brotman26
Estimated H-index: 26
+ 6 AuthorsEllen Leibenluft72
Estimated H-index: 72
Context Youth with bipolar disorder (BD) and those with severe, nonepisodic irritability (severe mood dysregulation [SMD]) exhibit amygdala dysfunction during facial emotion processing. However, studies have not compared such patients with each other and with comparison individuals in neural responsiveness to subtle changes in facial emotion; the ability to process such changes is important for social cognition. To evaluate this, we used a novel, parametrically designed faces paradigm. Objective...
32 Citations Source Cite