Archives of General Psychiatry
Papers 6812
1 page of 682 pages (6,812 results)
Published on Jan 1, 2013in Archives of General Psychiatry
Daphne-Zacharenia Kounali10
Estimated H-index: 10
(University of Bristol),
Stanley Zammit46
Estimated H-index: 46
(University of Bristol)
+ 2 AuthorsNicola Wiles31
Estimated H-index: 31
Published on Apr 1, 2012in Archives of General Psychiatry
Joel Swendsen8
Estimated H-index: 8
Marcy Burstein18
Estimated H-index: 18
+ 4 AuthorsKathleen R. Merikangas100
Estimated H-index: 100
Context Comprehensive descriptions of substance use and abuse trajectories have been lacking in nationally representative samples of adolescents. Objective To examine the prevalence, age at onset, and sociodemographic correlates of alcohol and illicit drug use and abuse among US adolescents. Design Cross-sectional survey of adolescents using a modified version of the Composite International Diagnostic Interview. Setting Combined household and school adolescent samples. Participants Nationally re...
175 Citations Source Cite
Published on Aug 1, 2012in Archives of General Psychiatry
David F. Tolin55
Estimated H-index: 55
(Yale University),
Michael C. Stevens52
Estimated H-index: 52
(Yale University)
+ 6 AuthorsGodfrey D. Pearlson106
Estimated H-index: 106
(Yale University)
Context Hoarding disorder (HD), previously considered a subtype of obsessive-compulsive disorder (OCD), has been proposed as a unique diagnostic entity in DSM-5. Current models of HD emphasize problems of decision-making, attachment to possessions, and poor insight, whereas previous neuroimaging studies have suggested abnormalities in frontal brain regions. Objective To examine the neural mechanisms of impaired decision making in HD in patients with well-defined primary HD compared with patients...
63 Citations Source Cite
Published on Dec 1, 2012in Archives of General Psychiatry
Mette Ødegaard Nielsen7
Estimated H-index: 7
Egill Rostrup44
Estimated H-index: 44
+ 5 AuthorsBirte Glenthøj35
Estimated H-index: 35
Context Schizophrenic symptoms are linked to a dysfunction of dopamine neurotransmission and the brain reward system. However, it remains unclear whether antipsychotic treatment, which blocks dopamine transmission, improves, alters, or even worsens the reward-related abnormalities. Objective To investigate changes in reward-related brain activations in schizophrenia before and after antipsychotic monotherapy with a dopamine D 2 /D 3 antagonist. Design Longitudinal cohort study. Setting Psychiatr...
80 Citations Source Cite
Published on Jul 1, 2012in Archives of General Psychiatry
Hanan El Marroun16
Estimated H-index: 16
Vincent W. V. Jaddoe72
Estimated H-index: 72
+ 7 AuthorsHenning Tiemeier74
Estimated H-index: 74
Objective: To examine the effects of maternal SSRI use during pregnancy on fetal growth and birth outcomes.
106 Citations Source Cite
Published on Jan 1, 2012in Archives of General Psychiatry
Panos Roussos35
Estimated H-index: 35
Pavel Katsel24
Estimated H-index: 24
+ 8 AuthorsLarry J. Siever82
Estimated H-index: 82
Context: Genetic, neuroimaging, and molecular neurobiological evidence support the hypothesis that the disconnectivity syndrome in schizophrenia (SZ) could arise from failures of saltatory conduction and abnormalities at the nodes of Ranvier (NOR) interface where myelin and axons interact. Objective: To identify abnormalities in the expression of oligodendroglial genes and proteins that participate in the formation, maintenance, and integrity of the NOR in SZ. Design: The messenger RNA (mRNA) ex...
77 Citations Source Cite
Published on Dec 1, 2012in Archives of General Psychiatry
Carl Ernst27
Estimated H-index: 27
(Broad Institute),
Christian R. Marshall46
Estimated H-index: 46
(University of Toronto)
+ 26 AuthorsVamsee Pillalamarri11
Estimated H-index: 11
(University of Ottawa)
Context Brain-derived neurotrophic factor (BDNF) is suspected of being a causative factor in psychiatric disorders based on case reports or studies involving large structural anomalies. Objective To determine the involvement of BDNF in human psychopathology. Design Case-control study. Setting Microarray-based comparative genomic hybridization data from 7 molecular diagnostic centers including 38 550 affected subjects and 28 705 unaffected subjects. Patients Subjects referred to diagnostic screen...
16 Citations Source Cite
Published on Nov 1, 2012in Archives of General Psychiatry
Rajendra A. Morey27
Estimated H-index: 27
(Duke University),
Andrea L. Gold13
Estimated H-index: 13
+ 6 AuthorsGregory McCarthy89
Estimated H-index: 89
Context Smaller hippocampal volumes are well established in posttraumatic stress disorder (PTSD), but the relatively few studies of amygdala volume in PTSD have produced equivocal results. Objective To assess a large cohort of recent military veterans with PTSD and trauma-exposed control subjects, with sufficient power to perform a definitive assessment of the effect of PTSD on volumetric changes in the amygdala and hippocampus and of the contribution of illness duration, trauma load, and depres...
120 Citations Source Cite
Published on Jul 1, 2012in Archives of General Psychiatry
Arpana Agrawal47
Estimated H-index: 47
Elliot C. Nelson43
Estimated H-index: 43
+ 10 AuthorsMichele L. Pergadia38
Estimated H-index: 38
Context The endocannabinoid system has been implicated in stress adaptation and the regulation of mood in rodent studies, but few human association studies have examined these links and replications are limited. Objectives To examine whether a synonymous polymorphism, rs1049353, in exon 4 of the gene encoding the human endocannabinoid receptor (CNR1) moderates the effect of self-reported childhood physical abuse on lifetime anhedonia and depression and to replicate this interaction in an indepen...
49 Citations Source Cite
Published on Jun 1, 2012in Archives of General Psychiatry
David M. Allen1
Estimated H-index: 1
Peter Parry7
Estimated H-index: 7
+ 5 AuthorsIrwin Feinberg36
Estimated H-index: 36
3 Citations Source Cite