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Cardiovascular Diabetology
IF
5.95
Papers
1755
Papers 1754
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#1Ki-Bum Won (UOU: University of Ulsan)H-Index: 6
Last. Hae Ok Jung (Catholic University of Korea)H-Index: 12
view all 11 authors...
BACKGROUND: Data on the relationship between the triglyceride glucose (TyG) index and coronary artery calcification (CAC) progression is limited. This longitudinal study evaluated the association of TyG index with CAC progression in asymptomatic adults. METHODS: We enrolled 12,326 asymptomatic Korean adults who had at least two CAC evaluations. The TyG index was determined using ln (fasting triglycerides [mg/dL] x fasting glucose [mg/dL]/2). CAC progression was defined as a difference >/= 2.5 be...
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#1Ying Tang (CSU: Central South University)H-Index: 1
#2Sheng-Lan Li (CSU: Central South University)
Last. Dan-Yan Xu (CSU: Central South University)H-Index: 1
view all 6 authors...
The proprotein convertase subtilisin/kexin type 9 (PCSK9) acts via a canonical pathway to regulate circulating low-density lipoprotein-cholesterol (LDL-C) via degradation of the LDL receptor (LDLR) on the liver cell surface. Published research has shown that PCSK9 is involved in atherosclerosis via a variety of non-classical mechanisms that involve lysosomal, inflammatory, apoptotic, mitochondrial, and immune pathways. In this review paper, we summarized these additional mechanisms and described...
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BACKGROUND: Biomarkers may contribute to our understanding of the pathophysiology of various diseases. Type 2 diabetes (T2D) and coronary heart disease (CHD) share many clinical and lifestyle risk factors and several biomarkers are associated with both diseases. The current analysis aims to assess the relevance of biomarkers combined to pathway groups for the development of T2D and CHD in the same cohort. METHODS: Forty-seven serum biomarkers were measured in the MONICA/KORA case-cohort study us...
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#1Bo Liang (Nanjing University of Chinese Medicine)
Last. Ning Gu (Nanjing University of Chinese Medicine)
view all 3 authors...
The study regarding load-independent effects of empagliflozin contribute to improved cardiac function in experimental heart failure with reduced ejection fraction is very interesting. But there are a few things we need to pay attention to.
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#1Xiaoteng Ma (Capital Medical University)H-Index: 1
#2Lisha Dong (Capital Medical University)
Last. Xiaoli Liu (Capital Medical University)H-Index: 8
view all 10 authors...
BACKGROUND: The triglyceride glucose (TyG) index, a simple surrogate estimate of insulin resistance, has been demonstrated to predict cardiovascular (CV) disease morbidity and mortality in the general population and many patient cohorts. However, to our knowledge, the prognostic usefulness of the TyG index after percutaneous coronary intervention (PCI) in patients with type 2 diabetes mellitus (T2DM) and acute coronary syndrome (ACS) has not been determined. This study aimed to evaluate the asso...
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#1Yi-Hsin Chan (CGU: Chang Gung University)H-Index: 7
#2Chi Chuang (Memorial Hospital of South Bend)
Last. Chi-Tai Kuo (CGU: Chang Gung University)H-Index: 21
view all 12 authors...
BACKGROUND: Studies specifically examining the association between glycated hemoglobin A1c (HbA1c) levels and ischemic stroke/systemic thromboembolism (IS/SE) risk in atrial fibrillation (AF) patients are limited. Here, we investigated the association between HbA1c levels and the risk of IS/SE, as well as major bleeding, among AF patients with or without oral anticoagulants (OACs). We also compared the effectiveness and safety of warfarin and direct oral anticoagulants (DOACs) in different HbA1c...
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#1Lin Zhu (UTS: University of Technology, Sydney)H-Index: 1
#2Andrew Hayen (UTS: University of Technology, Sydney)H-Index: 32
Last. Katy J. L. Bell (USYD: University of Sydney)H-Index: 13
view all 3 authors...
BACKGROUND: The Action to Control Cardiovascular Risk in Diabetes (ACCORD)-Lipid study found no evidence of a beneficial effect of statin-fibrate combined treatment, compared to statins alone, on cardiovascular outcomes and mortality in type 2 diabetes mellitus after 5 years of active treatment. However, a beneficial reduction in major CVD events was shown in a pre-specified sub-group of participants with dyslipidemia. The extended follow-up of this trial provides the opportunity to further inve...
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#1Svitlana DemyanetsH-Index: 17
#2Christoph KaunH-Index: 26
Last. Gersina Rega-KaunH-Index: 2
view all 9 authors...
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Top fields of study
Endocrinology
Type 2 diabetes
Angiology
Diabetes mellitus
Medicine