Environmental Toxicology and Pharmacology
Papers 3226
1 page of 323 pages (3,226 results)
#1Kapil Mandrah (IITR: Indian Institute of Toxicology Research)H-Index: 3
#2Veena Jain (IITR: Indian Institute of Toxicology Research)
Last. Somendu Kumar Roy (IITR: Indian Institute of Toxicology Research)H-Index: 6
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Abstract Previous studies highlighted bisphenol S (BPS), an industrial chemical responsible for harmful effects comparable to its congener substance bisphenol A (BPA). Accounted for various adversities to biological functions, it could alter the expression of endogenous metabolites in many metabolic processes. The study was aimed to investigate the altered metabolites in hyperglycemic condition triggered by sub-chronic exposure of BPS in serum and urine samples of Wistar rats. Invaded effects of...
#1Mayra P. Becerra-Amezcua (IPN: Instituto Politécnico Nacional)
#2Arisaí C. Hernández-Sámano (UNAM: National Autonomous University of Mexico)H-Index: 1
Last. Reyna C. Collí-Dulá (IPN: Instituto Politécnico Nacional)
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Abstract Pterois volitans venom induces muscular fibrillation, which results from nerve transmission caused by the presence of acetylcholine (ACh). It also has cardiovascular effects that are due to its actions on muscarinic and nicotinic cholinergic receptors. In this study, we characterized the effects of P. volitans venom on nicotinic acetylcholine receptors (nAChRs) and dopaminergic neurons. After exposure to P. volitans venom, acetylcholinesterase (AChE) mRNA levels and the expression of th...
#1Jana Blahova (VFU: University of Veterinary and Pharmaceutical Sciences Brno)H-Index: 17
#2Claudia Cocilovo (UNIME: University of Messina)
Last. Caterina Faggio (UNIME: University of Messina)H-Index: 37
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Abstract Triazine herbicide atrazine is considered to be moderately toxic to various aquatic animals. The aim of our study was to evaluate the acute embryotoxicity of atrazine and its two degradation products, desisopropylatrazine and desethylatrazine, and their mixture to the early life stages of zebrafish (Danio rerio) by means of a modified method of the Fish Embryo Acute Toxicity (FET) Test – OECD guideline 236. Toxic effects were studied by the evaluation of lethal endpoints and development...
#1Kareem M. Saad (Mansoura University)
#2Rehab S. Abdelrahman (Taibah University)H-Index: 1
Last. Eman Said (Mansoura University)H-Index: 9
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Abstract Cisplatin is an effective anticancer used widely in treatment of solid and germ cell tumors, however, the immense toxicity on healthy tissues discourages cisplatin use in prolonged treatment protocols. Testicular toxicity is amongst its undesired adverse effects. Nilotinib is a second generation multityrosine kinase inhibitor which is used as an anticancer agent with anti-inflammatory and antioxidant activities. In the present study, a single dose of cisplatin (7 mg/kg, I.P) to rats ind...
#1A. K. SoniH-Index: 1
#2A.S.B. Bhaskar (DRDE: Defence Research and Development Establishment)H-Index: 13
Last. G. M. KannanH-Index: 22
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Abstract Our previous study showed that percutaneous sulfur mustard (SM) exposure induced pulmonary toxicity, which was attenuated by DRDE-07 (S-2[2-aminoethylamino] ethyl phenyl sulphide) pretreatment. The present study aimed to evaluate the protective efficacy of DRDE-07 and its analogues viz., DRDE-30 (S-2(2-aminoethyl amino)ethyl propyl sulphide) and DRDE-35 (S-2(2-aminoethyl amino)ethyl butyl sulphide) against SM. Thirty minutes before percutaneous SM (0.8 LD50) exposure, female Swiss mice ...
#1Prithu Baruah (NEHU: North Eastern Hill University)
#2Neha Chaurasia (NEHU: North Eastern Hill University)H-Index: 2
Abstract Alpha-cypermethrin (ACy) is a synthetic pyrethroid insecticide commonly used in agricultural practices for controlling a broad range of insect pests particularly belonging to the order Lepidoptera and Coleoptera. The present study aims to evaluate the toxic effect of ACy on microalgae by studying its influence on Chlorella sp. According to our knowledge, this is the first detailed study of ACy toxicity on microalgae.Significant growth inhibition of Chlorella sp. was observed at high ACy...
#2Elke EilebrechtH-Index: 1
Last. Matthias G. Wacker (NUS: National University of Singapore)H-Index: 13
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Abstract Nanomaterials have gained huge importance in various fields including nanomedicine. Nanoformulations of drugs and nanocarriers are used to increase pharmaceutical potency. However, it was seen that polymeric nanomaterials can cause negative effects. Thus, it is essential to identify nanomaterials with the least adverse effects on aquatic organisms. To determine the toxicity of polymeric nanomaterials, we investigated the effects of poly(lactic-co-glycolid) acid (PLGA), Eudragit® E 100 a...
Abstract Environmental contaminants can deleteriously affect aquatic animals. One such contaminant is 5-fluorouracil (5-FU), a long-prescribed chemotherapeutic drug. Leucovorin (LV) is co-administered with 5-FU, potentiating its effects. Zebrafish (Danio rerio) larvae were reared in ng/L treatments of either 5-FU, LV, or a combined 5-FU/LV mixture for 8 dy. Survival was measured daily and swimming behavior assessed every other day. After 8 dy, larval length was measured, and densitometry of p53-...
#1Zuntao Wu (Zhengzhou University)H-Index: 1
#2Lin Bai (Zhengzhou University)
Last. Hui Huang (Zhengzhou University)H-Index: 6
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Abstract Lead (Pb) is recognized as a potent inducer of synaptic toxicity generally associated with reduced synaptic transmission and increased neuronal fiber excitability, becoming an environmental risk for neurodegenerative processes. Despite numerous toxicological studies on Pb have been directed to the developing brain, attention concerning long-term consequences of pubertal chronic Pb exposure on neuronal activity is still lacking. Thus, we exposed 4-week-old male mice to 0.2% lead acetate ...
Abstract Background Articles concerning the correlation of the risk of chronic kidney disease (CKD) with air contaminant exposure present inconsistent findings and the magnitude of the link is still unclear. Therefore, we planned to systematically and quantitatively investigate the overall strength of proofs in this field. Methods Relevant articles on Cochrane, EMBASE, Medline, Web of Science, and CINHAL were searched as per relevant strategies. Only observational studies that disclosed the link...
Top fields of study
Oxidative stress