The Cerebellum
Papers 1348
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#1Xiaofeng Lu (Juntendo University)H-Index: 17
#2Ken-ichi Inoue (Primate Research Institute)H-Index: 19
Last. Yusuke Uchida (Juntendo University)H-Index: 7
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The cerebellum and the basal ganglia play an important role in the control of voluntary eye movement associated with complex behavior, but little is known about how cerebellar projections project to cortical eye movement areas. Here we used retrograde transneuronal transport of rabies virus to identify neurons in the cerebellar nuclei that project via the thalamus to supplementary eye field (SEF) of the frontal cortex of macaques. After rabies injections into the SEF, many neurons in the restric...
#1Nils S. van den Berg (UvA: University of Amsterdam)
Last. Edward H.F. de HaanH-Index: 63
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An increasing amount of research has shown a cerebellar involvement in higher order cognitive functions, including emotional processing and decision-making. However, it has not been investigated whether impairments in facial emotion recognition, which could be a marker of impaired emotional experiences, are related to risky decision-making in these patients. Therefore, we aimed to investigate facial emotion recognition and risky decision-making in these patients as well as to investigate a relat...
#1Cláudia Lorea (UFPEL: Universidade Federal de Pelotas)
Last. Jonas Alex Morales SauteH-Index: 17
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#1Silvia PicazioH-Index: 9
#2Francesca Foti (Magna Græcia University)H-Index: 18
Last. Stefano SdoiaH-Index: 9
view all 7 authors...
The inhibitory mechanism named backward inhibition (BI) counteracts interference of previous tasks supporting task switching. For instance, if task set A is inhibited when switching to task B, then it should take longer to immediately return to task set A (as occurring in an ABA sequence), as compared to a task set that has not been just inhibited (as occurring in a CBA sequence), because extra time will be needed to overcome the inhibition of task set A. The evidenced prefrontal and cerebellar ...
#1Aasef G. ShaikhH-Index: 19
#2Mario Manto (University of Mons)H-Index: 33
Delay eyeblink conditioning (dEBC) is widely used to assess cerebellar-dependent associative motor learning, including precise timing processes. Transcranial direct current stimulation (tDCS), noninvasive brain stimulation used to indirectly excite and inhibit select brain regions, may be a promising tool for understanding how functional integrity of the cerebellum influences dEBC behavior. The aim of this study was to assess whether tDCS-induced inhibition (cathodal) and excitation (anodal) of ...
#1Sivan Jossinger (BIU: Bar-Ilan University)
#2Firas Mawase (Technion – Israel Institute of Technology)
Last. Lior Shmuelof (BGU: Ben-Gurion University of the Negev)H-Index: 12
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In sensorimotor adaptation paradigms, participants learn to adjust their behavior in response to an external perturbation. Locomotor adaptation and reaching adaptation depend on the cerebellum and are accompanied by changes in functional connectivity in cortico-cerebellar circuits. In order to gain a better understanding of the particular cerebellar projections involved in locomotor adaptation, we assessed the contribution of specific white matter pathways to the magnitude of locomotor adaptatio...
#1Alexey SedovH-Index: 2
#2Svetlana UsovaH-Index: 1
Last. Aasef G. ShaikhH-Index: 19
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The relationship between two common movement disorders, dystonia and tremor, is controversial. Both deficits have correlates in the network that includes connections between the cerebellum and the basal ganglia. In order to assess the physiological relationship between tremor and dystonia, we measured the activity of 727 pallidal single-neurons during deep brain stimulation surgery in patients with cervical dystonia without head oscillations, cervical dystonia plus jerky oscillations, and cervic...
#1Walter Oleschko Arruda (UFPR: Federal University of Paraná)H-Index: 16
#2Alex Tiburtino Meira (UFPR: Federal University of Paraná)H-Index: 1
Last. Hélio A.G. Teive (UFPR: Federal University of Paraná)H-Index: 27
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Spinocerebellar ataxias type 3 (SCA3) and type 10 (SCA10) are the most prevalent in southern Brazil. To analyze the relationships between volumetric MRI changes and clinical and genetic findings in SCA3 and SCA10 patients. All patients in the study had a confirmed genetic diagnosis. Demographic data, ataxia severity (SARA score), and the size of the expanded alleles were evaluated. Nineteen SCA3 and 18 SCA10 patients were selected and compared with a similar number of healthy controls. Patient a...
#1Hsu-Huai Chiu (NYMU: National Yang-Ming University)
#2Cheng-Tsung Hsaio (NTU: National Taiwan University)
Last. Bing-Wen SoongH-Index: 26
view all 6 authors...
Mutations in STUB1 have been identified to cause autosomal recessive spinocerebellar ataxia type 16 (SCAR16), also named as Gordon Holmes syndrome, which is characterized by cerebellar ataxia, cognitive decline, and hypogonadism. Additionally, several heterozygous mutations in STUB1 have recently been described as a cause of autosomal dominant spinocerebellar ataxia type 48. STUB1 encodes C-terminus of HSC70-interacting protein (CHIP), which functions as an E3 ubiquitin ligase and co-chaperone a...
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