Mediators of Inflammation
Papers 4311
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#2Lirong TanH-Index: 1
Last. Cong PengH-Index: 8
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Psoriasis is a common immune-mediated, chronic inflammatory genetic-related disease that affects patients’ quality of life. Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of progenitor and immature myeloid cells which are expanded in psoriatic skin lesions and peripheral blood. However, the role of MDSCs in the pathogenesis of psoriasis remains unclear. Here, we confirmed that the accumulation of human MDSCs is remarkably increased in skin lesions of psoriasis patients b...
#1Hua Bai (Nanjing University of Chinese Medicine)H-Index: 1
#2Sen-Lei Xu (Nanjing University of Chinese Medicine)H-Index: 1
Last. Sheng-Feng Lu (Nanjing University of Chinese Medicine)H-Index: 3
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#1Mingxia Zhao (Capital Medical University)
#2Houzhen Tuo (Capital Medical University)H-Index: 4
Last. Lin Zhao (Capital Medical University)
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Sleep disorder significantly affects the life quality of a large number of people but is still an underrecognized disease. Dietary nutrition is believed to play a significant impact on sleeping wellness. Many nutritional supplements have been used trying to benefit sleep wellness. However, the relationship between nutritional components and sleep is complicated. Nutritional factors vary dramatically with different diet patterns and depend significantly on the digestive and metabiotic functions o...
Inflammation is a key regulator in the progression of atherosclerosis (AS) which extremely affects people’s health. Secoisolariciresinol diglucoside (SDG), a plant lignan, is relevant to angiogenesis and cardioprotection against ischemia-reperfusion injury and improves vascular disorders. However, the effect of SDG on cardiovascular disorder is not clear. In the present study, we aimed to investigate the effects of SDG on lipopolysaccharide- (LPS-) stimulated Human Umbilical Vein Endothelial Cel...
#1Skyla A. Duncan (Alabama State University)H-Index: 4
#2Rajnish Sahu (Alabama State University)H-Index: 12
Last. Vida A. Dennis (Alabama State University)H-Index: 27
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The immunopathology of chlamydial diseases is exacerbated by a broad-spectrum of inflammatory mediators, which we reported are inhibited by IL-10 in macrophages. However, the chlamydial protein moiety that induces the inflammatory mediators and the mechanisms by which IL-10 inhibits them are unknown. We hypothesized that Chlamydia major outer membrane protein (MOMP) mediates its disease pathogenesis, and the suppressor of cytokine signaling (SOCS)1 and SOCS3 proteins are mediators of the IL-10 i...
#1Duraisamy Kempuraj (MU: University of Missouri)H-Index: 37
#2Mohammad Ejaz Ahmed (MU: University of Missouri)H-Index: 9
Last. Asgar Zaheer (MU: University of Missouri)H-Index: 29
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Traumatic brain injury (TBI) is one of the major health problems worldwide that causes death or permanent disability through primary and secondary damages in the brain. TBI causes primary brain damage and activates glial cells and immune and inflammatory cells, including mast cells in the brain associated with neuroinflammatory responses that cause secondary brain damage. Though the survival rate and the neurological deficiencies have shown significant improvement in many TBI patients with newer...
#1Francisco Monsalve (University of Talca)H-Index: 4
#2Armando RojasH-Index: 22
Last. Fernando Delgado-LópezH-Index: 4
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Receptor internalization and degradation (RID), is a transmembrane protein coded within the E3 region expression cassette of adenoviruses. RID downregulates the cell surface expression of epidermal growth factor receptor (EGFR), tumor necrosis factor receptor (TNFR), and apoptosis antigen 1 (FAS), causing a reduction of the effects of their respective ligands. In addition, RID inhibits apoptosis by decreasing the secretion of TNF-related apoptosis-inducing ligand (TRAIL) by normal tissue cells. ...
#1Sandrine Cabantous (AMU: Aix-Marseille University)H-Index: 12
#2Belco PoudiougouH-Index: 15
Last. Sandrine Marquet (AMU: Aix-Marseille University)H-Index: 17
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Background. Cerebral malaria (CM), a reversible encephalopathy affecting young children, is a medical emergency requiring rapid clinical assessment and treatment. However, understanding of the genes/proteins and the biological pathways involved in the disease outcome is still limited. Methods. We have performed a whole transcriptomic analysis of blood samples from Malian children with CM or uncomplicated malaria (UM). Hierarchical clustering and pathway, network, and upstream regulator analyses ...
#1Beata Smok (UMK: Nicolaus Copernicus University in Toruń)H-Index: 2
#2Krzysztof Domagalski (UMK: Nicolaus Copernicus University in Toruń)H-Index: 7
Last. Małgorzata Pawłowska (UMK: Nicolaus Copernicus University in Toruń)H-Index: 12
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#1Yunxia Dong (PRC: China Medical University (PRC))H-Index: 2
#2Wei Hong (LNUTCM: Liaoning University of Traditional Chinese Medicine)
Last. Hongtao Liu (PRC: China Medical University (PRC))H-Index: 3
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