International Journal of Obesity
Papers 8397
1 page of 840 pages (8,397 results)
#1Tomáš Suchý (Leipzig University)
#2Christian Zieschang (Leipzig University)
Last. John Andrew Pospisilik (Van Andel Institute)H-Index: 1
view all 17 authors...
G protein-coupled receptors (GPCR) are well-characterized regulators of a plethora of physiological functions among them the modulation of adipogenesis and adipocyte function. The class of Adhesion GPCR (aGPCR) and their role in adipose tissue, however, is poorly studied. With respect to the demand for novel targets in obesity treatment, we present a comprehensive study on the expression and function of this enigmatic GPCR class during adipogenesis and in mature adipocytes. The expression of all...
#1Andrea Di Nisio (UNIPD: University of Padua)H-Index: 8
#2Iva Sabovic (UNIPD: University of Padua)H-Index: 3
Last. Carlo Foresta (UNIPD: University of Padua)H-Index: 54
view all 8 authors...
The recognized association between male hypogonadism and obesity has multifactorial implications on adipose tissue (AT) physiology. The fat solubility of testosterone (T) suggests a sequestration process in fat depots, leading to reduced circulating levels of T in obesity. Several evidence suggest that steroids play a two-sided inhibitory role on adipogenesis by locally decreasing lipid accumulation and by stimulating lipolysis. The current study investigates T trafficking and activity in dysfun...
#1Yi-hong Li (SYSU: Sun Yat-sen University)
#2Ting-yu Sun (SYSU: Sun Yat-sen University)
Last. Yu-ming Chen (SYSU: Sun Yat-sen University)H-Index: 28
view all 7 authors...
Previous studies have reported that high-dose supplementation of n-3 polyunsaturated fatty acids (PUFAs) may reduce the risk of metabolic diseases, but there is limited evidence of an effect on body fat. We examined the associations of erythrocyte n-3 PUFAs with body fat and fat distribution in a general population consuming a normal diet. This community-based cross-sectional study included 3075 Chinese (68% women, 40–75 years) recruited between 2008 and 2013. We collected general information an...
#1Jodie M. Dodd (University of Adelaide)H-Index: 36
#2Andrea R Deussen (University of Adelaide)H-Index: 11
Last. Jennie Louise (University of Adelaide)H-Index: 6
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While the effects of an antenatal dietary intervention for women with obesity or overweight on pregnancy and newborn health have been extensively studied, the longer-term effects into childhood are unknown. We followed children born to women who participated in the LIMIT randomised trial, where pregnant women were randomised to an antenatal dietary and lifestyle intervention or standard antenatal care. Our aim was to assess the effect of the intervention, on child outcomes at 3–5 years of age on...
#1Suocheng Hui (Third Military Medical University)H-Index: 4
#2Yang Liu (Third Military Medical University)H-Index: 1
Last. Mantian Mi (Third Military Medical University)H-Index: 30
view all 9 authors...
Current evidence has linked dietary resveratrol (RSV) intake to the activation of brown adipose tissue (BAT) and induction of white adipose tissue (WAT) browning, which may be a potential means of improving glucose homeostasis. However, the underlying mechanisms remain unclear. A diet containing RSV was fed to db/db mice for 10 weeks, following which the body weight, adipose tissue accumulation, bile acid (BA) profiles, and markers of BA metabolism were analyzed. Oral glucose tolerance testing, ...
#1Qingqing Lv (PRC: China Medical University (PRC))
#2Aolin Yang (PRC: China Medical University (PRC))
Last. Difei Wang (PRC: China Medical University (PRC))H-Index: 1
view all 7 authors...
The orphan nuclear receptor Nur77 is an important factor regulating metabolism. Nur77 knockout mice become obese with age, but the cause of obesity in these mice has not been fully ascertained. We attempted to explain the cause of obesity in Nur77 knockout mice from the perspective of the gut microbiota and to investigate the inhibitory effect of calcipotriol combined with BRD9 inhibitor (iBRD9) on obesity. Eight-week-old wild-type mice and Nur77 knockout C57BL/6J mice were treated with calcipot...
#1Nicole Vogelzangs (UM: Maastricht University)H-Index: 42
#3Carla J.H. van der Kallen (UM: Maastricht University)H-Index: 32
Last. Simone J. P. M. Eussen (UM: Maastricht University)H-Index: 22
view all 16 authors...
Recent evidence indicates that insulin resistance (IR) in obesity may develop independently in different organs, representing different etiologies toward type 2 diabetes and other cardiometabolic diseases. The aim of this study was to investigate whether IR in the liver and IR in skeletal muscle are associated with distinct metabolic profiles. This study includes baseline data from 634 adults with overweight or obesity (BMI ≥ 27 kg/m2) (≤65 years; 63% women) without diabetes of the European Diog...
1 CitationsSource
#1Daniela de Barros Mucci (University of Cambridge)
#2Laura C. Kusinski (University of Cambridge)H-Index: 2
Last. Susan E. Ozanne (University of Cambridge)H-Index: 71
view all 10 authors...
In utero exposure to obesity is consistently associated with increased risk of metabolic disease, obesity and cardiovascular dysfunction in later life despite the divergence of birth weight outcomes. The placenta plays a critical role in offspring development and long-term health, as it mediates the crosstalk between the maternal and fetal environments. However, its phenotypic and molecular modifications in the context of maternal obesity associated with fetal growth restriction (FGR) remain poo...
#1Despoina ManousakiH-Index: 1
#2Sanyath RadjiH-Index: 1
Last. Melanie HendersonH-Index: 1
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1 Citations
#1Surabhi Bhutani (SDSU: San Diego State University)H-Index: 15
#2Nicole Wells (SDSU: San Diego State University)
Last. Dale A. Schoeller (UW: University of Wisconsin-Madison)H-Index: 79
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The winter holiday season in the United States, which spans mid-November to mid-January, contributes to over half of annual body weight gain. Although self-reported data have linked this weight change to both increased energy intake and reduced physical activity, objective techniques have never been used; and thus, the actual cause of holiday weight gain is controversial. Here, we aimed to determine changes in components of energy balance leading to the holiday weight gain. Body weight change wa...
Top fields of study
Body mass index
Diabetes mellitus