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International Journal of Obesity
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#1Elizabeth Sanchez-Rangel (Yale University)H-Index: 1
#2Jean-Dominique Gallezot (Yale University)H-Index: 20
Last.Janice J. Hwang (Yale University)H-Index: 6
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The energy-dissipating properties of brown adipose tissue (BAT) have been proposed as therapeutic targets for obesity and diabetes. Little is known about basal BAT activity. Capitalizing on the dense sympathetic innervation of BAT, we have previously shown that BAT can be detected in humans under resting room temperature (RT) conditions by using (S,S)-11C–O-methylreboxetine (MRB), a selective ligand for the norepinephrine transporter (NET). In this study, we determine whether MRB labeling of hum...
#1Marte Karoline Råberg Kjøllesdal (University of Oslo)H-Index: 7
#2Inger Ariansen (FHI: Norwegian Institute of Public Health)H-Index: 8
Last.Øyvind Næss (University of Oslo)H-Index: 24
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The time between early adulthood and midlife is important for obesity development. There is paucity of studies using objectively measured body mass index (BMI) at both time points with full range of midlife cardiovascular risk factors. We aimed to investigate the risk of cardiovascular disease (CVD) mortality associated with different levels of objectively measured change in body weight from early adulthood to midlife, and to assess whether risk is primarily explained by midlife cardiovascular r...
#1Rosa Rodríguez Rodríguez (ULL: University of La Laguna)
#2Antonio Gonzalez-Bulnes (Complutense University of Madrid)H-Index: 3
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The pathogenesis of renal disease in the context of overweight/obesity, metabolic syndrome, and insulin resistance is not completely understood. This may be due to the lack of a definitive animal model of disease, which limits our understanding of obesity-induced renal damage. We evaluated the changes in renal histology and lipid deposits induced by obesity in a model of insulin resistance: the Iberian swine fed with fat-enriched food. Twenty-eight female sows were randomized to standard (SD) or...
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