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Clinical Nutrition
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Summary Background Acute pancreatitis (AP) is marked by a strong pro-inflammatory response, which may cause a systemic inflammatory response syndrome (SIRS), organ failure, and death. Early administration of omega-3 fatty acids (FA) may reduce the pro-inflammatory response and improve outcome in AP. A systematic review focusing on the safety and efficacy of omega-3 FA in AP is lacking. Aim Evaluate the safety and efficacy of an intervention with omega-3 FA in acute pancreatitis and sepsis. Metho...
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Summary Background and Aims Segmental estimates add specificity to body composition evaluation and could potentially have greater health and function implications than whole-body estimates alone. The aim of this study was to quantify the level of agreement between total and segmental fat mass (FM) and lean soft tissue (LST) estimates from dual-energy x-ray absorptiometry (DXA) and single-frequency bioelectrical impedance analysis (SFBIA). Methods Assessments via DXA (GE® Lunar Prodigy) and SFBIA...
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Summary Background & aims There have been inconsistent findings on the association between dietary patterns and depressive symptoms (DepS). In addition, studies have used single analysis methods to identify dietary patterns. In the current study, we aimed to determine the association between dietary patterns, derived by principal component analysis (PCA), reduced-rank regressions (RRR) and partial least-squares (PLS), and DepS among adults using a cohort study in Australia. Methods We examined a...
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Summary Background Sarcopenia and cognitive impairment are two of the most prevalent causes of disability in the aging population. Despite the vast amount of research that has been done to quantify the association between these two conditions, extensive systematic reviews and meta-analyses remain limited. Methods We performed a systematic review using the PubMed, EMBASE, Scopus, and Google Scholar databases. Sarcopenia was defined as the loss of skeletal muscle mass and muscle function, as measu...
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Summary Background and aims Chemoradiation and bioradiation (CRT/BRT) for locally advanced head and neck squamous cell carcinoma (LAHNSCC) often comes with high toxicity rates, interfering with oral intake and leading to temporary tube feeding (TF) dependency. High-quality scientific evidence for indicators of prophylactic gastrostomy insertion is not available. The aim of this retrospective cohort study was to develop a prediction model to identify patients who need prophylactic gastrostomy ins...
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Summary Background The effects of low-protein diet (LPD) on kidney function and nutrition in nephropathy are so far unclear. Objective To investigate the effect of LPD on kidney function and nutrition. Data sources PubMed, Embase and Cochrane library up to January 2019 and references of retrieved relevant articles. Result Twenty-nine studies with 1784 individuals in the LPD arm and 1782 individuals in the normal protein diet were identified. Compared with normal protein diet, LPD significantly r...
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Summary Background & Aims Alterations in body hydration can have an impact on muscle performance, with consequences not only at a sporting level, but on overall health and daily functional competence. Given that the estimation of body water from BIA is based on prediction equations involving assumptions on tissue hydration and body geometry, it is unclear if phase angle (PhA), which is not influenced by assumptions, is a better marker of muscle performance than the BIA estimated parameters of bo...
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Summary Background & aims Metabolic flexibility is the ability to adapt fuel oxidation to fuel availability. Metabolic inflexibility has been associated with obesity, the metabolic syndrome and insulin resistance, and can be improved by exercise or weight loss. Dietary changes can modulate metabolic flexibility; however, the effect of a whole diet approach on metabolic flexibility has never been studied. Therefore, our objective was to assess the effect of a healthy diet (HD), as compared to a t...
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Summary Introduction The Nutritional Risk Screening 2002 (NRS 2002) identifies patients at risk of malnutrition. We studied the prognostic implications of this score with regard to short-term and long-term clinical outcomes in a well-characterised cohort of medical inpatients from a previous trial. Methods This is a secondary analysis of an investigator-initiated, prospective randomised controlled multicenter trial in Switzerland (EFFORT) that compared the effects of an individualised nutritiona...
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Summary Background & aims Elderly patients are being increasingly admitted to the intensive care unit (ICU) for mechanical ventilation (MV) and prevalence of decreased skeletal muscle mass which develop with aging is subsequently increasing. The objective of this study was to identify the association between decreased skeletal muscle mass and extubation failure in patients undergoing long-term MV. Methods Adults (≥18 years of age) with long-term MV for > 7 days between January 2014 and February ...
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Top fields of study
Endocrinology
Intensive care medicine
Diabetes mellitus
Medicine
Parenteral nutrition