BioMed Research International
Papers 18575
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#1Aditi Chauhan (Panjab University, Chandigarh)H-Index: 1
#2Vijay Prabha (Panjab University, Chandigarh)H-Index: 10
The present study was carried out to assess the contraceptive efficacy of sperm agglutinating factor (SAF) isolated from Serratia marcescens, in male Balb/c mice. Mice were administered via an intratesticular route with different concentrations of SAF, viz., 10, 50, 100, 200, or 400 µg, in the right testis only which served as a test while the left side served as control except otherwise stated. Mice were sacrificed on day 3, 7, 14, 21, 30, 45, 60, and 90 after administration, and results in ter...
#1Yuanyuan Nie (JLU: Jilin University)
#2Yan Jiao (JLU: Jilin University)
Last.Wei Li (JLU: Jilin University)
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A refined liver cancer staging system and effective prognostic prediction can help clinicians make optimized treatment decisions, which is essential in our fight against cancer and for improving the unsatisfying survival rate of liver cancer globally. The prognosis of liver cancer is not only related to tumor status, it is also affected by the patients’ liver functions and the chosen treatment. Currently, several staging systems are being tested. Herein, we analyzed RNA-seq data from the TCGA da...
#1Xue-ting Li (HMU: Harbin Medical University)
#2Zibo Yan (CDC: Centers for Disease Control and Prevention)
Last.Kaijiang Yu (HMU: Harbin Medical University)H-Index: 5
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Purpose. Mean platelet volume (MPV) and platelet distribution width (PDW) have been used to reflect the platelet activity in clinics. We assessed initial serum MPV and PDW levels in colorectal cancer (CRC) patients, in predicting the development of sepsis in CRC patients postoperatively. Patients and Methods. This study included 220 patients diagnosed with CRC. 55 patients were stratified to one group that developed sepsis postoperatively, and 165 patients were stratified to the other group that...
#2Rui Wang (BSU: Beijing Sport University)
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Osteoarthritis (OA) is one of the major diseases leading to disability, and inflammation plays an important role in the pathogenesis of OA. However, inflammation of OA is multifactorial, chronic, and in low intensity, which makes drug-based immunotherapy difficult. Here, we have designed a novel method of exercise—static low angle squat (SLAS), which reduces the intra-articular inflammation of OA knee as well as strengthens the vastus medialis of quadriceps. A two-year follow-up trial of current...
There is a substantial use of pesticides within the agricultural industry of Chile, with neurotoxic effects through mechanisms of acetylcholinesterase inhibition. These pesticides result in deterioration in health, increasing the risk of diseases such as Parkinson’s and Alzheimer’s in highly exposed occupational population. To date, there are no brief assessment tools to monitor cognitive impairment in agricultural workers chronically exposed to these pesticides. Method. 234 agricultural workers...
#1Xiaoyu Xi (Sichuan Agricultural University)H-Index: 1
#2Qin Zou (Sichuan Agricultural University)H-Index: 2
Last.Yanzhi Jiang (Sichuan Agricultural University)H-Index: 10
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The biological function of human ovaries declines along with aging. To identify the underlying molecular changes during ovarian aging, pigs were used as model animals. Genome-wide DNA methylation and transcriptome-wide RNA expression analyses were performed via high-throughput sequencing of ovaries from young pigs (180 days, puberty stage of first ovulation) and old pigs (eight years, reproductive exhaustion stage). The results identified 422 different methylation regions between old and young p...
#1Liu Peng (STU: Shantou University)
#2Jin-Cheng Guo (STU: Shantou University)H-Index: 7
Last.En-Min Li (STU: Shantou University)H-Index: 22
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Flavoproteins and their interacting proteins play important roles in mitochondrial electron transport, fatty acid degradation, and redox regulation. However, their clinical significance and function in esophageal squamous cell carcinoma (ESCC) are little known. Here, using survival analysis and machine learning, we mined 179 patient expression profiles with ESCC in GSE53625 from the Gene Expression Omnibus (GEO) database and constructed a signature consisting of two flavoprotein genes (GPD2 and ...
#1Mitsuru Nakazawa (Hirosaki University)H-Index: 29
#2Aiko Hara (Hirosaki University)
Last.Sei-ichi Ishiguro (Tohoku University)H-Index: 18
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Purpose. The aim of this study was to understand the relationship between the findings of spectral-domain optical coherence tomography (SD-OCT) of previously reported animal models of retinitis pigmentosa (RP) associated with known genetic mutations and their background structural and functional changes. Methods. We reviewed previous publications reporting the SD-OCT findings of animal models of RP and summarized the characteristic findings of SD-OCT in nine different animal models (RCS–/–, RHO ...
#1Guo ChenH-Index: 3
#2Bin Xu (Sichuan University)H-Index: 5
Last.Fuxing Pei (Sichuan University)H-Index: 23
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Background. Upper partial fibulectomy has been preliminarily proved to have the efficacy for pain alleviation and improvement of function in patients with mild to moderate medial compartment knee osteoarthritis (KOA). However, the previous studies lack the control group with other treatments. The aim of this prospective, randomized controlled study is to compare the clinical and biomechanical effects between upper partial fibulectomy and drug conservative treatment on improvement of clinical pai...
#1Julia Maasjost (FU: Free University of Berlin)
#2Dörte Lüschow (FU: Free University of Berlin)H-Index: 9
Last.Kristin Mühldorfer (FU: Free University of Berlin)H-Index: 3
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Virulence-associated traits have frequently been studied in enterococci and are considered to contribute towards the pathogenicity of infections. In the present study, Enterococcus isolates were collected during diagnostic investigations from meat turkeys in Germany. Twenty-eight isolates of three different Enterococcus species were analyzed for five selected putative virulence traits to understand their potential role in the pathogenicity using the chicken embryo lethality assay. Ten E. faecali...
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Diabetes mellitus