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Laura Maggino
University of Verona
SurgeryPancreatectomyPancreatic fistulaGeneral surgeryMedicine
73Publications
10H-index
379Citations
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Publications 78
Newest
#1Bofeng Chen (UPenn: University of Pennsylvania)H-Index: 2
#2Maxwell T. Trudeau (UPenn: University of Pennsylvania)
Last. Charles M. Vollmer (UPenn: University of Pennsylvania)H-Index: 40
view all 11 authors...
Background Hyperbilirubinemia is commonly observed in patients requiring pancreatoduodenectomy (PD). Thus far, literature regarding the danger of operating in the setting of hyperbilirubinemia is equivocal. What remains undefined is at what specific level of bilirubin there is an adverse safety profile for undergoing PD. The aim of this study is to identify the optimal safety profile of patients with hyperbilirubinemia undergoing PD.
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#1Giuseppe Malleo (University of Verona)H-Index: 29
#2Laura Maggino (University of Verona)H-Index: 10
Last. Keith D. Lillemoe (Harvard University)H-Index: 96
view all 13 authors...
BACKGROUND: The authors hypothesized that in resected pancreatic adenocarcinoma (PDAC), pathologic characteristics, oncologic outcomes, prognostic factors, and the accuracy of the American Joint Committee on Cancer (AJCC) staging system might differ based on tumor location. METHODS: Patients undergoing pancreatectomy for PDAC at two academic institutions from 2000 to 2015 were retrieved. A comparative analysis between head (H-PDAC) and body-tail (BT-PDAC) tumors was performed using uni- and mult...
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#1Giuseppe Malleo (University of Verona)H-Index: 29
#2Laura Maggino (University of Verona)H-Index: 10
Last. Giovanni Marchegiani (University of Verona)H-Index: 19
view all 12 authors...
Abstract Background The pattern of nodal spread in body-tail pancreatic ductal adenocarcinoma (PDAC) has been poorly investigated. This study analyzed the characteristics of lymph node (LN) involvement and the prognostic role of nodal metastases stratified by LN stations. Methods All upfront distal pancreatectomies (DPs) for PDAC (2000–2017) with complete information on station 8,10,11, and 18 were included. Clinico-pathological correlates and survival were investigated using uni- and multivaria...
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#1Giampaolo Perri (University of Texas MD Anderson Cancer Center)
#2Laura Reka Prakash (University of Texas MD Anderson Cancer Center)H-Index: 9
Last. Laura MagginoH-Index: 10
view all 18 authors...
BACKGROUND: The incidence and magnitude of indicators of radiographic response of pancreatic cancer to systemic chemotherapy and (chemo)radiation administered prior to anticipated pancreatectomy are unclear. METHODS: Sequential computed tomography scans of 226 patients with localized pancreatic cancer who received chemotherapy consisting of 5-fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFIRINOX) or gemcitabine and nanoparticle albumin-bound paclitaxel (GA) with or without (chemo)rad...
1 CitationsSource
#1Giuseppe MalleoH-Index: 29
#1Giuseppe Malleo (Harvard University)
Last. Roberto SalviaH-Index: 37
view all 4 authors...
Source
#1Maxwell T. Trudeau (UPenn: University of Pennsylvania)
#2Laura Maggino (UPenn: University of Pennsylvania)H-Index: 10
Last. Charles M. Vollmer (UPenn: University of Pennsylvania)H-Index: 40
view all 4 authors...
Purpose This study aimed to identify optimal management decisions for surgeons preforming pancreatic head resection on patients with altered anatomy due to a previous Roux-en-Y gastric bypass (RYGB).
Source
OBJECTIVE: To test the hypothesis that complete, tumor-free resection at the pancreatic neck, achieved either en-bloc or non-en-bloc (ie, revision based on intraoperative frozen section [FS] analysis), is associated with improved survival as compared with incomplete resection (IR) in pancreatic ductal adenocarcinoma. SUMMARY BACKGROUND DATA: Given the likely systemic nature of pancreatic ductal adenocarcinoma, the oncologic benefit of achieving a histologically complete local resection, particul...
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#1Giuseppe MalleoH-Index: 29
#2Laura MagginoH-Index: 10
Last. Roberto SalviaH-Index: 37
view all 11 authors...
3 CitationsSource
#1Laura Maggino (UPenn: University of Pennsylvania)H-Index: 10
#2Jason B. Liu (U of C: University of Chicago)H-Index: 6
Last. Charles M. Vollmer (UPenn: University of Pennsylvania)H-Index: 40
view all 6 authors...
Abstract Background The association between higher surgical volume and better perioperative outcomes after pancreatectomy has been extensively demonstrated. However, how different notions of experience impact outcomes of surgeons operating within high-quality scenarios remains unclear. Methods Self-reported experience parameters from ACS-NSQIP HPB-Collaborative surgeons were merged with 2014–2016 ACS-NSQIP clinical data. The association of various experience parameters with outcomes was investig...
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#1Laura Maggino (University of Verona)H-Index: 10
#2Giuseppe Malleo (University of Verona)H-Index: 4
Last. Roberto Salvia (University of Verona)H-Index: 37
view all 24 authors...
Importance Chemotherapy is the recommended induction strategy in borderline resectable and locally advanced pancreatic ductal adenocarcinoma. However, the associated results on an intention-to-treat basis are poorly understood. Objective To investigate pragmatically the treatment compliance, conversion to surgery, and survival outcomes of patients with borderline resectable and locally advanced pancreatic ductal adenocarcinoma undergoing primary chemotherapy. Design, Setting, and Participants Th...
4 CitationsSource
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