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Todd J. Schwedt
Mayo Clinic
Physical therapyMigraineHeadachesAnesthesiaMedicine
172Publications
28H-index
3,067Citations
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Publications 198
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PURPOSE OF REVIEW: Posttraumatic headache (PTH) attributed to mild traumatic brain injury is common and debilitating. In up to one-half of those with acute PTH, the PTH becomes persistent (PTH), enduring for longer than 3 months. The high incidence and persistence of PTH necessitate research into PTH pathophysiology and treatment. In this review, recent developments regarding the diagnostic criteria for PTH, the pathophysiology of PTH, and PTH treatment are discussed. RECENT FINDINGS: Internatio...
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#2Shweta Shah (Amgen)
Last. Todd J. Schwedt (Mayo Clinic)H-Index: 28
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BACKGROUND: Migraine is associated with debilitating symptoms that can affect daily functioning. "My Migraine Voice" was a large, cross-sectional, multi-country online survey aimed at understanding disease burden directly from people with migraine. OBJECTIVE: This study reports on the social and economic impacts of migraine, specifically the impact on activities of daily living and the costs of migraine, from the point of view of people with migraine in the United States. METHODS: The online sur...
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#1Kim Sk (Gyeongsang National University)
#2Catherine D. Chong (Mayo Clinic)H-Index: 12
Last. Todd J. Schwedt (Mayo Clinic)H-Index: 28
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BACKGROUND: Close associations between insomnia with other clinical factors have been identified in migraine, but there have been few studies investigating associations between insomnia and clinical factors in patients with persistent post-traumatic headache (PPTH). The study objective was to contrast the severity of insomnia symptoms in PPTH, migraine, and healthy controls, and to identify factors associated with insomnia in patients with PPTH vs. migraine. METHODS: In this cross-sectional coho...
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#1Dawn C. Buse (Albert Einstein College of Medicine)H-Index: 36
#2Michael L. ReedH-Index: 34
Last. Richard B. Lipton (Albert Einstein College of Medicine)H-Index: 97
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BACKGROUND: Migraine has many presumed comorbidities which have rarely been compared between samples with and without migraine. Examining the association between headache pain intensity and monthly headache day (MHD) frequency with migraine comorbidities is novel and adds to our understanding of migraine comorbidity. METHODS: The MAST Study is a prospective, web-based survey that identified US population samples of persons with migraine (using modified International Classification of Headache Di...
1 CitationsSource
#1Sagar Munjal (Princeton University)H-Index: 6
#2Preeti Singh (Princeton University)H-Index: 1
Last. Richard B. Lipton (Albert Einstein College of Medicine)H-Index: 97
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OBJECTIVES: The objectives of this study were to determine the rates of nausea, phonophobia, and photophobia reported overall and as the most bothersome symptom (MBS) in individuals with migraine and to identify individual characteristics associated with each of the 3 candidate MBSs. BACKGROUND: The MBS has emerged as an important coprimary efficacy endpoint in clinical trials of acute treatments for migraine, as recommended by the Food and Drug Administration. The current understanding of how p...
1 CitationsSource
#1Todd J. Schwedt (Mayo Clinic)H-Index: 28
#2Kathleen B. Digre (UofU: University of Utah)H-Index: 38
Last. David William Dodick (Mayo Clinic)H-Index: 68
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BACKGROUND: The American Registry for Migraine Research (ARMR) is a multicenter, prospective, longitudinal patient registry, biorepository, and neuroimaging repository that collects clinical data, electronic health record (EHR) data, blood samples, and brain imaging data from individuals with migraine or other headache types. In this manuscript, we outline ARMR research methods and report baseline data describing an initial cohort of ARMR participants. METHODS: Adults with any International Clas...
1 CitationsSource
#1Talia A. Pearl (WashU: Washington University in St. Louis)
#2Gina Dumkrieger (Mayo Clinic)H-Index: 3
Last. Todd J. Schwedt (Mayo Clinic)H-Index: 28
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BACKGROUND AND OBJECTIVES: Migraine with aura (MwA) is associated with increased brain hyper-responsiveness to visual stimuli and increased visual network connectivity relative to migraine without aura (MwoA). Despite this, prior studies have provided conflicting results regarding whether MwA is associated with higher photophobia symptom scores compared to MwoA. The relationships between MwA and other types of sensory hypersensitivity, such as phonophobia and cutaneous allodynia (CA), have not b...
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#1Catherine D. Chong (Mayo Clinic)H-Index: 12
Last. Todd J. Schwedt (Mayo Clinic)H-Index: 28
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OBJECTIVES: The hypothalamus plays a key role in both migraine and cluster headache (CH). As brain region-to-region structural correlations are believed to reflect structural and functional brain connectivity patterns, we assessed the structural covariance patterns between the volume of the hypothalamic region and vertex-by-vertex measurements of cortical thickness in patients with migraine and in those with CH relative to healthy controls (HC). METHODS: T1-weighted images were acquired on a 3T ...
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#1Fu-Chi Yang (NDMC: National Defense Medical Center)
#2Todd J. Schwedt (Mayo Clinic)H-Index: 28
Last. Shuu-Jiun Wang (NYMU: National Yang-Ming University)H-Index: 57
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Migraine and cluster headache (CH) are complex disorders characterized by recurrent episodes of headache. Although the two are regarded as distinct primary headache disorders, the clinical boundaries between CH and migraine are sometimes poorly defined, and there can be considerable overlap between the characteristics of the two headache types. Given the inherent clinical variability in these two headache disorders, it is likely that some patients will exhibit overlapping symptoms of CH and migr...
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#1Paolo MartellettiH-Index: 32
#2Todd J. Schwedt (Mayo Clinic)H-Index: 28
Last. Annik K. Laflamme (Novartis)H-Index: 2
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Objectives As part of the worldwide My Migraine Voice survey, this study evaluated the real-world healthcare resource utilization (HRU) and impact on work and activity impairment among people living with migraine in the United Kingdom (UK). Methods An analysis was conducted using UK subset data from My Migraine Voice survey: a worldwide, cross-sectional, online study including respondents (≥18 years), with ≥4 monthly migraine days, with 90% having used preventive migraine treatment in the preced...
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