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Ghasem Hosseini Salekdeh
Macquarie University
ProteomeMolecular biologyProteomicsBiologyCell biology
191Publications
39H-index
4,618Citations
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Publications 199
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#1Javad Gharechahi (BMSU: Baqiyatallah University of Medical Sciences)H-Index: 11
Last. Ghasem Hosseini SalekdehH-Index: 39
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The attachment of rumen microbes to feed particles is critical to feed fermentation, degradation and digestion. However, the extent to which the physicochemical properties of feeds influence the colonization by rumen microbes is still unclear. We hypothesized that rumen microbial communities may have differential preferences for attachments to feeds with varying lignocellulose properties. To this end, the structure and composition of microbial communities attached to six common forages with diff...
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#1Leila Ghanbari Maman (UT: University of Tehran)
#2Fahimeh Palizban (UT: University of Tehran)
Last. Kaveh Kavousi (UT: University of Tehran)H-Index: 6
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Rumen microbial environment hosts a variety of microorganisms that interact with each other to carry out the feed digestion and generation of several by-products especially methane, which plays an essential role in global warming as a greenhouse gas. However, due to its multi-factorial nature, the exact cause of methane production in the rumen has not yet been fully determined. The current study is an attempt to use system modeling to analyze the relationship between interacting components of ru...
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#1Morteza MalekiH-Index: 1
#2Mehdi Foroozandeh Shahraki (UT: University of Tehran)
Last. Ghasem Hosseini Salekdeh (Macquarie University)H-Index: 39
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Abstract Lignocellulose is the most abundant biomass in nature, and the effective biorefining of them is dependent upon enzymes with high catalytic activity and stability in extreme pH and high temperatures. Due to the molecular constraints for a single enzyme, obtaining a more excellent active pH range can be more easily achievable through the simultaneous activity of two or more enzymes in a cocktail. To address this, we attempted to develop a cocktail of novel thermostable cellulases with hig...
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Abstract Oligodendrocyte precursor cells (OPCs) are ideal therapeutic cells for treatment of spinal cord injuries and diseases that affect myelin. However, it is necessary to generate a cell population with a low risk of teratoma formation and oncogenesis from a patient’s somatic cells. In this study, we investigated the direct reprogramming of fibroblasts to oligodendrocyte-like cells in one step with a safe non-genetic delivery method that used protein transduction. Cell morphology and the lin...
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#2E. MotamediH-Index: 9
Last. Ghasem Hosseini Salekdeh (Macquarie University)H-Index: 39
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Abstract This study indicated tailoring efficient polymer-enzyme bioconjugates with superb stability and activity for practical utilization of cellulase enzyme in hydrolyzing lignocellulosic biomass. To this goal, a dual crosslinking (DC) strategy was presented to synthesize novel 3D networks of carboxymethyl cellulose grafted copolymers of 2-acrylamido-2methyl propane sulfonate and acrylamide (CMC-g-poly(AMPS-co-AAm)) hydrogels. Graphene oxide (GO) nano-sheets were utilized as nano-filler and p...
1 CitationsSource
#1Parisa KoobazH-Index: 4
Last. Ghasem Hosseini Salekdeh (Macquarie University)H-Index: 39
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Abstract Young wheat seedlings are desiccation tolerant and have the capacity to withstand long dehydration period. In this study, we characterized the proteome and metabolome of wheat seedlings during desiccation and after recovery. Functional classification of differentially identified proteins revealed dynamic changes in the number and abundance of proteins observed during stress and recovery. Desiccation resulted in a decline in the abundance of proteins associated with photosynthesis and ca...
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#1Anna Meyfour (Shahid Beheshti University of Medical Sciences and Health Services)H-Index: 2
#2Sara Pahlavan (Royan Institute)H-Index: 6
Last. Ghasem Hosseini Salekdeh (Macquarie University)H-Index: 39
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Despite the small number of Y chromosome genes, their adequate expression is required for regulation of transcription, translation, and protein stability in males, not just for sex determination. In addition to the role in male fertility, the Y chromosome has a significant role in the development and sexual dimorphism of healthy and disease phenotypes. We observed that KDM5D along with its X-counterpart, KDM5C, are up-regulated during the cardiac mesoderm stage of development. Down-regulation of...
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#1Sara Taleahmad (Royan Institute)H-Index: 4
#2Mehdi Alikhani (Royan Institute)H-Index: 8
Last. Ghasem Hosseini Salekdeh (Macquarie University)H-Index: 39
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Although males and females have a variety of sexually dimorphic features related to hormonal effects, the genetic basis of dimorphism relies on early embryo development. Two pluripotent states, naive and primed, emerge during early mammalian development. Identification of signaling pathways that induce differences between these two states can help to modulate conversion of primed cells to naive cells. Naive cells have a shorter doubling time and longer survival than their primed counterparts whe...
1 CitationsSource
#2Elnaz Hosseini (UT: University of Tehran)H-Index: 2
Last. Ghasem Hosseini Salekdeh (Macquarie University)H-Index: 39
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Abstract Enzyme immobilization onto supports could improve its specificity, storage stability, reusability, pH tolerance and thermal stability. Aiming to provide a proficient immobilization carrier for a recombinant xylanase (PersiXyn1), the high-performance 3D copolymeric network of carboxymethyl cellulose (CMC)-based hydrogel sponges were synthesized using in situ graft radical polymerization. While typical purified gel drying in a vacuum oven made CMC/Acrylate-Hydrogel, the freeze-drying of t...
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