Alessio Aghemo
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Publications 334
#1Serena Pelusi (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico)H-Index: 13
#2Guido Alessandro Baselli (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico)H-Index: 4
Last.Luca Valenti (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico)H-Index: 48
view all 22 authors...
Nonalcoholic fatty liver disease (NAFLD) is a rising cause of hepatocellular carcinoma (HCC). We examined whether inherited pathogenic variants in candidate genes (n = 181) were enriched in patients with NAFLD-HCC. To this end, we resequenced peripheral blood DNA of 142 NAFLD-HCC, 59 NAFLD with advanced fibrosis, and 50 controls, and considered 404 healthy individuals from 1000 G. Pathogenic variants were defined according to ClinVar, likely pathogenic as rare variants predicted to alter protein...
4 CitationsSource
#1Luca Di TommasoH-Index: 24
#2M. SpadacciniH-Index: 3
Last.Ana LleoH-Index: 37
view all 7 authors...
#1Ashley Brown (Imperial College Healthcare)H-Index: 19
#2Tania M. Welzel (Goethe University Frankfurt)H-Index: 26
Last.Tarik Asselah (University of Paris)H-Index: 54
view all 15 authors...
#1Luca Valenti (University of Milan)H-Index: 48
#2Alessio Aghemo (Humanitas University)H-Index: 29
Last.Alejandro Forner (University of Barcelona)H-Index: 30
view all 3 authors...
#1G. Tosetti (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico)H-Index: 6
#2Massimo Primignani (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico)H-Index: 34
Last.Pietro Lampertico (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico)H-Index: 41
view all 14 authors...
Abstract Background Liver stiffness measurement (LSM) 150,000/mm3 exclude varices needing treatment (VNT) in viral compensated advanced chronic liver disease (cACLD), saving-up to 20–25% endoscopies (Baveno VI criteria). Refinements of such criteria to further reduce endoscopies and an approach without LSM (Platelet 150/MELD 6) were later proposed. Aims To assess LSM 25/platelet 125, LSM 25/platelet 110 (Expanded-Baveno VI) and Platelet 150/MELD 6 accuracy versus Baveno VI criteria, and the impa...
1 CitationsSource
#1M. Spadaccini (Humanitas University)H-Index: 3
#2Alessio Aghemo (Humanitas University)H-Index: 29
Last.Maria Francesca Donato (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico)H-Index: 14
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BackgroundThe management of inflammatory bowel disease in patients who have previously undergone liver transplantation can be a clinical challenge. There are serious concerns among physicians regar...
#1Elisabetta Degasperi (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico)H-Index: 11
#2A. SpinettiH-Index: 11
Last.Stefano FagiuoliH-Index: 37
view all 35 authors...
Background & Aims Sofosbuvir/velpatasivr/voxilaprevir (SOF/VEL/VOX) is approved for retreatment of patients with HCV and a previous failure on direct-acting antivirals (DAAs), however real-life data are limited. The aim of this study was to assess the effectiveness and safety of SOF/VEL/VOX in a real-life setting. Methods All consecutive patients with HCV receiving SOF/VEL/VOX between May-October 2018 in 27 centers in Northern Italy were enrolled. Bridging fibrosis (F3) and cirrhosis (F4) were d...
#1Giulia RodaH-Index: 17
#2Ana Lleo (Humanitas University)H-Index: 37
Last.Alessio Aghemo (Humanitas University)H-Index: 29
view all 4 authors...
#1Lorenza RimassaH-Index: 25
#2Nicola Personeni (Humanitas University)H-Index: 8
Last.Ana Lleo (Humanitas University)H-Index: 37
view all 4 authors...
Abstract Cholangiocarcinoma (CCA) is a deadly cancer of the biliary epithelium with limited therapeutic options. It is a heterogeneous group of cancer that could develop at any level from the biliary tree and is currently classified into intrahepatic, perihilar and distal based on its anatomical location. With incidence and mortality rates currently increasing, it is now the second most common type of primary liver cancer and represents up to 3% of all gastrointestinal malignancies. High-through...
2 CitationsSource
#1Stefan Zeuzem (Goethe University Frankfurt)H-Index: 5
#2Stefan BourgeoisH-Index: 10
Last.Michael Biermer (Janssen Pharmaceutica)H-Index: 1
view all 21 authors...
1 CitationsSource