Jim Lagopoulos
University of Sydney
PsychiatryPsychologyNeuroscienceBipolar disorderClinical psychology
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Publications 219
#1Lara M. Wierenga (LEI: Leiden University)H-Index: 4
#2Gaelle E. Doucet (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 17
Last. Ole A. Andreassen (University of Oslo)H-Index: 89
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For many traits, males show greater variability than females, with possible implications for understanding sex differences in health and disease. Here, the ENIGMA (Enhancing Neuro Imaging Genetics through Meta-Analysis) Consortium presents the largest-ever mega-analysis of sex differences in variability of brain structure, based on international data spanning nine decades of life. Subcortical volumes, cortical surface area and cortical thickness were assessed in MRI data of 16,683 healthy indivi...
Abstract The importance of sleep for mental health has been known for some time. Although it was initially suggested that mental health conditions negatively impact sleep, it is now widely understood that this association is bidirectional. Adolescence is a period where people are at an increased risk of being sleep deprived largely due to a late shift in the circadian rhythm around puberty combined with early school start times. Combined these may lead to adolescents being at an increased risk o...
Research shows that adolescents with mental illnesses have a bias for processing negative facial emotions, and this may play a role in impaired social functioning that often co-exists with a mental health diagnosis. This study examined associations between psychological and somatic problems and facial emotion recognition in early adolescence; as any processing biases in this age-group may be an early indicator of later mental illnesses. A community sample of 40 12-year-olds self-rated their symp...
1 CitationsSource
#1Elizabeth M. Scott (USYD: University of Sydney)H-Index: 38
Last. Ian B. HickieH-Index: 82
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Abstract A key population-health priority is to reduce the rates of premature death and illness burden due to the common anxiety and mood disorders that typically have their onset during adolescence and early-adult years. From an individual clinical and health services planning perspective, evidence relating to the potential impacts of early identification, secondary prevention, and enhanced long-term care strategies is required. Over the past decade, we have accumulated substantial cross-sectio...
#1Glenn HolmesH-Index: 1
#2Amanda ClacyH-Index: 5
Last. Jim LagopoulosH-Index: 40
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The practice of educating individuals (known as ‘gatekeepers’ [GK]) at the informal social level with the knowledge, skills, and confidence to identify an at-risk individual and provide support has...
1 CitationsSource
#2Amanda BoyesH-Index: 1
Last. Daniel F. HermensH-Index: 38
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1 CitationsSource
#1Laura S. van Velzen (University of Melbourne)H-Index: 8
#2Sinead Kelly (Brigham and Women's Hospital)H-Index: 14
Last. Lianne Schmaal (University of Melbourne)H-Index: 22
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Alterations in white matter (WM) microstructure have been implicated in the pathophysiology of major depressive disorder (MDD). However, previous findings have been inconsistent, partially due to low statistical power and the heterogeneity of depression. In the largest multi-site study to date, we examined WM anisotropy and diffusivity in 1305 MDD patients and 1602 healthy controls (age range 12–88 years) from 20 samples worldwide, which included both adults and adolescents, within the MDD Worki...
3 CitationsSource
#1Kristie Leigh Smith (USYD: University of Sydney)H-Index: 5
#2Mustafa S. Kassem (USYD: University of Sydney)H-Index: 4
Last. Jonathon C. Arnold (USYD: University of Sydney)H-Index: 28
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Abstract Few animal models exist that successfully reproduce several core associative and non-associative behaviours relevant to post-traumatic stress disorder (PTSD), such as long-lasting fear reactions, hyperarousal, and subtle attentional and cognitive dysfunction. As such, these models may lack the face validity required to adequately model pathophysiological features of PTSD such as CNS grey matter loss and neuroinflammation. Here we aimed to investigate in a mouse model of PTSD whether con...
#1Carolien G.F. de Kovel (MPG: Max Planck Society)H-Index: 30
Last. Clyde Francks (MPG: Max Planck Society)H-Index: 42
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Objective:Asymmetry is a subtle but pervasive aspect of the human brain, and it may be altered in several psychiatric conditions. MRI studies have shown subtle differences of brain anatomy between ...