Gordon H. Guyatt
McMaster University
Publications 1801
#2Mohit BhandariH-Index: 82
Last.Jordi Tomas-HernandezH-Index: 1
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Summary Background Observational studies have suggested that accelerated surgery is associated with improved outcomes in patients with a hip fracture. The HIP ATTACK trial assessed whether accelerated surgery could reduce mortality and major complications. Methods HIP ATTACK was an international, randomised, controlled trial done at 69 hospitals in 17 countries. Patients with a hip fracture that required surgery and were aged 45 years or older were eligible. Research personnel randomly assigned ...
1 CitationsSource
#1I Sessler DanielH-Index: 102
#2Daniel I. SesslerH-Index: 6
Last.Alben SigamaniH-Index: 16
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#1Sharon L. Kolasinski (UPenn: University of Pennsylvania)H-Index: 8
#2Tuhina Neogi (BU: Boston University)H-Index: 47
Last.James Reston (ECRI Institute)H-Index: 18
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1 CitationsSource
#1Achintya Dinesh Singh (Cleveland Clinic)
#2Agrima Mian (Cleveland Clinic)
Last.Ganesan Karthikeyan (AIIMS: All India Institute of Medical Sciences)H-Index: 34
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Aim Patients with severe mitral stenosis (MS) and their clinicians typically choose percutaneous transvenous mitral commissurotomy (PTMC) over surgical commissurotomy (SC). However, the durability of PTMC relative to SC is uncertain. We compared the efficacy, safety and durability of PTMC with SC for the treatment of MS. Methods We searched EMBASE, MEDLINE and WHO ICTRP registers for randomised controlled trials (RCTs) comparing PTMC, and open and/or closed mitral commissurotomy. The principal o...
#1Emmanuelle Duceppe (Population Health Research Institute)H-Index: 6
#2Ameen Patel (McMaster University)H-Index: 16
Last.Philip J. Devereaux (Population Health Research Institute)H-Index: 74
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1 CitationsSource
#1Fiona G. Kouyoumdjian (McMaster University)H-Index: 4
#2Ji Yun Lee (McMaster University)
Last.Gordon H. Guyatt (McMaster University)H-Index: 201
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We aimed to compare 30-day readmission after medical-surgical hospitalization for people who experience imprisonment and matched people in the general population in Ontario, Canada. We used linked population-based correctional and health administrative data. Of people released from Ontario prisons in 2010, we identified those with at least one medical or surgical hospitalization between 2005 and 2015 while they were in prison or within 6 months after release. For those with multiple eligible hos...
#1Marie-Hélène Masse (Centre Hospitalier Universitaire de Sherbrooke)H-Index: 3
#2Julie Ménard (Centre Hospitalier Universitaire de Sherbrooke)H-Index: 13
Last.Francois Lamontagne (Centre Hospitalier Universitaire de Sherbrooke)H-Index: 29
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Background Sepsis is a health problem of global importance; treatments focus on controlling infection and supporting failing organs. Recent clinical research suggests that intravenous vitamin C may decrease mortality in sepsis. We have designed a randomized controlled trial (RCT) to ascertain the effect of vitamin C on the composite endpoint of death or persistent organ dysfunction at 28 days in patients with sepsis.
#2S. Oczkowski (McMaster University)
Last.Maurizio CecconiH-Index: 32
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Objective To develop evidence-based clinical practice recommendations regarding transfusion practices in non-bleeding, critically ill adults.
#1Zhikang Ye (McMaster University)H-Index: 1
#2Annika Reintam Blaser (UT: University of Tartu)H-Index: 13
Last.Reed A C Siemieniuk (McMaster University)H-Index: 21
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Abstract Clinical question What is the role of gastrointestinal bleeding prophylaxis (stress ulcer prophylaxis) in critically ill patients? This guideline was prompted by the publication of a new large randomised controlled trial. Current practice Gastric acid suppression with proton pump inhibitors (PPIs) or histamine-2 receptor antagonists (H2RAs) is commonly done to prevent gastrointestinal bleeding in critically ill patients. Existing guidelines vary in their recommendations of which populat...
#1Ying Wang (Capital Medical University)H-Index: 2
#2Zhikang Ye (McMaster University)H-Index: 1
Last.Lihong Liu (Capital Medical University)H-Index: 3
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Abstract Objective To determine, in critically ill patients, the relative impact of proton pump inhibitors (PPIs), histamine-2 receptor antagonists (H2RAs), sucralfate, or no gastrointestinal bleeding prophylaxis (or stress ulcer prophylaxis) on outcomes important to patients. Design Systematic review and network meta-analysis. Data sources Medline, PubMed, Embase, Cochrane Central Register of Controlled Trials, trial registers, and grey literature up to March 2019. Eligibility criteria for sele...