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Jaakko Tuomilehto
National Institute for Health and Welfare
EndocrinologyType 2 diabetesPopulationDiabetes mellitusMedicine
1,671Publications
185H-index
173kCitations
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Publications 1705
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#1Asma Ahmed (Aga Khan University)H-Index: 1
#1Asma Ahmed (Aga Khan University)H-Index: 3
Last. Jaakko Tuomilehto (National Institute for Health and Welfare)H-Index: 185
view all 10 authors...
Background: We aimed to assess the burden of metabolic syndrome (MetS), and evaluate the phenotypic variation of MetS in a population at high risk for diabetes in urban Karachi, Pakistan. Methods: This study was embedded in a lifestyle intervention trial for the prevention of type 2 diabetes mellitus. The study population comprised participants who belonged to urban households in Karachi, Pakistan. Results: Among 15,590 individuals who were screened through diabetes risk score (DRS), 3945 indivi...
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#1Mahmoud IbrahimH-Index: 5
#2Melanie J. Davies (University of Leicester)H-Index: 82
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Fasting the Holy month of Ramadan constitutes one of the five pillars of the Muslim faith. Although there is some evidence that intermittent fasting during Ramadan may be of benefit in losing weight and cardiometabolic risk factors, there is no strong evidence these benefits apply to people with diabetes. The American Diabetes Association/European Association for the Study of Diabetes consensus recommendations emphasize the importance of patient factors and comorbidities when choosing diabetes m...
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#1Mahmoud IbrahimH-Index: 5
#2Jason Baker (Cornell University)
Last. Dario Tuccinardi (Sapienza University of Rome)H-Index: 6
view all 18 authors...
Hypoglycemia is common in patients with type 1 diabetes (T1D) and type 2 diabetes (T2D) and constitutes a major limiting factor in achieving glycemic control among people with diabetes. While hypoglycemia is defined as a blood glucose level under 70 mg/dL (3.9 mmol/L), symptoms may occur at higher blood glucose levels in individuals with poor glycemic control. Severe hypoglycemia is defined as an episode requiring the assistance of another person to actively administer carbohydrate, glucagon, or...
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#1R. Gabriel (ISCIII: Carlos III Health Institute)H-Index: 15
Last. Predrag B. DjordjevićH-Index: 1
view all 23 authors...
Objectives To assess the effects of early management of hyperglycaemia with antidiabetic drugs plus lifestyle intervention compared with lifestyle alone, on microvascular function in adults with pre-diabetes. Methods Trial design: International, multicenter, randomised, partially double-blind, placebo-controlled, clinical trial. Participants Males and females aged 45–74 years with IFG, IGT or IFG+IGT, recruited from primary care centres in Australia, Austria, Bulgaria, Greece, Kuwait, Poland, Se...
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#1Jaakko Tuomilehto (UH: University of Helsinki)H-Index: 185
Last. Lars C. Stene (FHI: Norwegian Institute of Public Health)H-Index: 37
view all 4 authors...
Epidemiological data on pediatric type 1 diabetes (T1D), mainly incidence, have become increasingly available since the second half of the 20th century. Comparative incidence data across populations were only obtained since the 1980s. The 2019 IDF Atlas provides T1D incidence, prevalence and mortality estimates for children < 15 years for all 211 countries, but actual data were available for only 94 countries (only 3 low-income). The estimated prevalent cases were 600,900 and incident cases 98,2...
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#1Suhad Bahijri (KAU: King Abdulaziz University)H-Index: 14
#2Rajaa Al-Raddadi (KAU: King Abdulaziz University)H-Index: 11
Last. Jaakko Tuomilehto (National Institute for Health and Welfare)H-Index: 185
view all 8 authors...
AIMS/INTRODUCTION: To develop a non-invasive risk score to identify Saudis having prediabetes or undiagnosed type 2 diabetes. METHODS: Adult Saudis without diabetes were recruited randomly using a stratified two-stage cluster sampling method. Demographic, dietary, lifestyle variables, personal and family medical history were collected using a questionnaire. Blood pressure and anthropometric measurements were taken. Body mass index was calculated. The 1-h oral glucose tolerance test was carried o...
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#1Prashantha Hebbar (UH: University of Helsinki)H-Index: 1
#2Mohamed Abu-FarhaH-Index: 15
Last. Abdullah BennakhiH-Index: 10
view all 16 authors...
Consanguineous populations of the Arabian Peninsula, which has seen an uncontrolled rise in type 2 diabetes incidence, are underrepresented in global studies on diabetes genetics. We performed a genome-wide association study on the quantitative trait of fasting plasma glucose (FPG) in unrelated Arab individuals from Kuwait (discovery-cohort:n = 1,353; replication-cohort:n = 1,196). Genome-wide genotyping in discovery phase was performed for 632,375 markers from Illumina HumanOmniExpress Beadchip...
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#2Abdullah AlkandariH-Index: 2
Last. Jaakko Tuomilehto (National Institute for Health and Welfare)H-Index: 185
view all 8 authors...
Abstract Background Diabetes is prevalent in Kuwait. We aimed to assess the level of glycemic control in Kuwaiti adults with diabetes. Methods The World Health Organization’s STEPS non-communicable disease risk factor survey was conducted in Kuwait in 2014. Participants’ demographics, medical history, physical measurements and blood biochemistry were assessed. A total of 2561 Kuwaiti men and women aged 18–69 years completed all three survey steps. Glycemic control in 278 individuals with diabete...
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#1Peter Nilsson (Lund University)H-Index: 106
#2Jaakko Tuomilehto (National Institute for Health and Welfare)H-Index: 185
Last. Lars Rydén (KI: Karolinska Institutet)H-Index: 6
view all 3 authors...
A cluster of metabolic factors have been merged into an entity named the metabolic syndrome. Although the characteristics of this syndrome have varied over time the presently used definition was es...
1 CitationsSource
#1Sina KavalakattH-Index: 9
#2Abdelkrim KhadirH-Index: 9
Last. Ali TissH-Index: 17
view all 9 authors...
Urocortin3 (UCN3) regulates metabolic functions and is involved in cellular stress response. Although UCN3 is expressed in human adipose tissue, the association of UCN3 with obesity and diabetes remains unclear. This study investigated the effects of Type 2 diabetes (T2D) and increased body weight on the circulatory and subcutaneous adipose tissue (SAT) levels of UCN3 and assessed UCN3 modulation by a regular physical exercise. Normal-weight (n = 37) and overweight adults with and without T2D (n...
1 CitationsSource
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