Hanna-Maaria Lakka
University of Eastern Finland
EndocrinologyMetabolic syndromePopulationDiabetes mellitusMedicine
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Publications 49
#1Juuso Väistö (University of Eastern Finland)H-Index: 7
#2Eero A. Haapala (University of Jyväskylä)H-Index: 10
Last. Timo A. Lakka (University of Eastern Finland)H-Index: 80
view all 12 authors...
6 CitationsSource
#1Aino-Maija Eloranta (University of Eastern Finland)H-Index: 10
#2Ursula Schwab (University of Eastern Finland)H-Index: 40
Last. Virpi Lindi (University of Eastern Finland)H-Index: 26
view all 8 authors...
Abstract Background and aims There are no studies on the relationships of dietary quality indices to the clustering of cardiometabolic risk factors in children. We therefore investigated the associations of four dietary quality indices with cardiometabolic risk score and cardiometabolic risk factors in Finnish children. Methods and results Subjects were a population sample of 204 boys and 198 girls aged 6–8 years. We assessed diet by 4-day food records and calculated Dietary Approaches to Stop H...
3 CitationsSource
#1Janine F. Felix (EUR: Erasmus University Rotterdam)H-Index: 14
#2Jonathan P. Bradfield (Center for Applied Genomics)H-Index: 49
Last. Vincent W. V. Jaddoe (EUR: Erasmus University Rotterdam)H-Index: 78
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A large number of genetic loci are associated with adult body mass index. However, the genetics of childhood body mass index are largely unknown. We performed a meta-analysis of genome-wide association studies of childhood body mass index, using sex- and age-adjusted standard deviation scores. We included 35 668 children from 20 studies in the discovery phase and 11 873 children from 13 studies in the replication phase. In total, 15 loci reached genome-wide significance (P-value < 5 × 10(-8)) in...
111 CitationsSource
#1Hanna-Maaria LakkaH-Index: 26
#2Timo A. LakkaH-Index: 2
Last. Jukka T. SalonenH-Index: 10
view all 5 authors...
Background: The role of hyperinsulinemia as a cardiovascular risk factor is controversial. We studied whether hyperinsulinemia is independently associated with increased cardiovascular morbidity and mortality. Methods: Fasting serum insulin level and other cardiovascular risk factors were determined in 1521 men in eastern Finland aged 42 to 60 years with neither cardiovascular disease nor diabetes at baseline. Forty-five cardiovascular deaths, 110 acute coronary events, 48 strokes, and 163 any c...
14 Citations
#1Tuomo Tompuri (University of Eastern Finland)H-Index: 13
#2Timo A. Lakka (University of Eastern Finland)H-Index: 80
Last. Tomi Laitinen (University of Eastern Finland)H-Index: 22
view all 9 authors...
Summary Objective and methods We compared InBody720 segmental multifrequency bioimpedance analysis (SMF-BIA) with Lunar Prodigy Advance dual-energy X-ray absorptiometry (DXA) in assessment of body composition among 178 predominantly prepubertal children. Segmental agreement analysis of body compartments was carried out, and inter-relationships of anthropometric and other measures of body composition were defined. Moreover, the relations of different reference criteria for excess body fat were ev...
38 CitationsSource
#1Aino-Maija Eloranta (University of Eastern Finland)H-Index: 10
#2Virpi Lindi (University of Eastern Finland)H-Index: 26
Last. Timo A. Lakka (University of Eastern Finland)H-Index: 80
view all 8 authors...
Purpose Previous evidence for the associations of eating frequency and food consumption with clustering of metabolic risk factors among children is limited. We therefore investigated association of the daily number of main meals and snacks and food consumption with a metabolic risk score and individual metabolic risk factors in primary school children.
19 CitationsSource
#1Juuso Väistö (University of Eastern Finland)H-Index: 7
#2Aino-Maija Eloranta (University of Eastern Finland)H-Index: 10
Last. Timo A. Lakka (University of Eastern Finland)H-Index: 80
view all 12 authors...
Background Lower levels of physical activity (PA) and sedentary behaviour (SB) have been associated with increased cardiometabolic risk among children. However, little is known about the independent and combined associations of PA and SB as well as different types of these behaviours with cardiometabolic risk in children. We therefore investigated these relationships among children.
64 CitationsSource
#1Anna Viitasalo (University of Eastern Finland)H-Index: 11
#2Timo A. Lakka (University of Eastern Finland)H-Index: 80
Last. Rainer RauramaaH-Index: 66
view all 11 authors...
Aims/hypothesis We validated the metabolic syndrome (MetS) score by confirmatory factor analysis (CFA) in children, middle-aged men, and older women and men and by investigating the relationships of the MetS score to incident type 2 diabetes, myocardial infarction, and cardiovascular and overall death in middle-aged men.
49 CitationsSource
#1Anu VierolaH-Index: 4
#2Anna L. SuominenH-Index: 13
Last. Timo A. LakkaH-Index: 80
view all 9 authors...
The last two coauthors (Matti Narhi and Timo Lakka) share the last authorship. Aims: To examine the prevalence and significance of clinically determined signs of temporomandibular disorders (TMD) and pain in different parts of the body as well as the frequency, intensity, and other features of pain in children. Methods: The subjects were a population-based sample of children 6 to 8 years of age. Complete data on clinical signs of TMD were available for 483 children. Data on pain during the past ...
#1Maarit ValtonenH-Index: 5
#2David E. Laaksonen (University of Eastern Finland)H-Index: 55
Last. Jussi Kauhanen (University of Eastern Finland)H-Index: 48
view all 9 authors...
Aim: Abundant evidence suggests that depression is a risk factor for cardiovascular disease and metabolic syndrome. Systemic low-grade inflammation and evolving abdominal obesity are hypothesised to be underlying mechanisms explaining the relationship. To test this hypothesis we examined the association of depressive symptoms and inflammation in developing abdominal obesity. Methods: The subjects were 726 non-diabetic men, 42–60 of age at baseline, participating in the Kuopio Ischemic Heart Dise...
17 CitationsSource