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Peter Sasieni
Queen Mary University of London
250Publications
50H-index
9,285Citations
Publications 257
Newest
#1Avi Rosenfeld (UCL: University College London)H-Index: 1
#2D Graham (UCL: University College London)H-Index: 3
Last.Sharon CaveH-Index: 1
view all 90 authors...
Summary Background Screening for Barrett's oesophagus relies on endoscopy, which is invasive and few who undergo the procedure are found to have the condition. We aimed to use machine learning techniques to develop and externally validate a simple risk prediction panel to screen individuals for Barrett's oesophagus. Methods In this prospective study, machine learning risk prediction in Barrett's oesophagus (MARK-BE), we used data from two case-control studies, BEST2 and BOOST, to compile trainin...
1 CitationsSource
#1Peter Sasieni ('KCL': King's College London)H-Index: 50
#2Jack Cuzick (QMUL: Queen Mary University of London)H-Index: 117
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#1Rebecca Landy (QMUL: Queen Mary University of London)H-Index: 1
#2Peter Sasieni ('KCL': King's College London)H-Index: 50
Last.Cosette M. Wheeler (UNM: University of New Mexico)H-Index: 72
view all 10 authors...
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#1Jinshuo Li (Ebor: University of York)H-Index: 9
#2Peter Hajek (QMUL: Queen Mary University of London)H-Index: 44
Last.Steve Parrott (Ebor: University of York)H-Index: 23
view all 14 authors...
Aim To evaluate the cost-effectiveness of e-cigarettes as a smoking cessation aid used in routine stop smoking service. Design Cost-effectiveness analysis was performed from the National Health Service (NHS) and Personal Social Services (PSS) perspective for 12 months period and lifetime. Costs, including that of both treatments, other smoking cessation help and healthcare services, and health benefits, estimated from EQ-5D-5L and measured in Quality-adjusted Life years (QALYs), for the 12-month...
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#1RW Lee (The Royal Marsden NHS Foundation Trust)
#2A Nair (UCL: University College London)
Last.David R Baldwin (NUH: Nottingham University Hospitals NHS Trust)H-Index: 32
view all 8 authors...
Introduction The NLST and NELSON studies demonstrated lung cancer mortality reduction from low-dose CT (LDCT) lung cancer screening. Local implementation pilots of ‘Lung Health Checks’ indicate feasibility in the NHS. NHS England will now fund 10 aligned projects for a national Lung Health Check pilot as a major centre-piece of the early diagnosis agenda of the NHS Long Term Plan. We report on methodological approaches to deliver this project and progress towards deployment. Methods Sites select...
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#1Bernard V. North (QMUL: Queen Mary University of London)H-Index: 14
#2HemantMKocher (QMUL: Queen Mary University of London)H-Index: 31
Last.Peter Sasieni (QMUL: Queen Mary University of London)H-Index: 50
view all 3 authors...
A key challenge in phase I trials is maintaining rapid escalation in order to avoid exposing too many patients to sub-therapeutic doses, while preserving safety by limiting the frequency of toxic events. Traditional rule-based designs require temporarily stopping recruitment whilst waiting to see whether enrolled patients develop toxicity. This can be both inefficient and introduces logistic challenges to recruitment in the clinic. We describe a novel two-stage dose assignment procedure designed...
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#1Peter Sasieni ('KCL': King's College London)H-Index: 50
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#1Melina Arnold (IARC: International Agency for Research on Cancer)H-Index: 17
#2Mark J. Rutherford (IARC: International Agency for Research on Cancer)H-Index: 11
Last.Freddie Ian Bray (IARC: International Agency for Research on Cancer)H-Index: 88
view all 38 authors...
Summary Background Population-based cancer survival estimates provide valuable insights into the effectiveness of cancer services and can reflect the prospects of cure. As part of the second phase of the International Cancer Benchmarking Partnership (ICBP), the Cancer Survival in High-Income Countries (SURVMARK-2) project aims to provide a comprehensive overview of cancer survival across seven high-income countries and a comparative assessment of corresponding incidence and mortality trends. Met...
12 CitationsSource
#1Rengaswamy Sankaranarayanan (IARC: International Agency for Research on Cancer)H-Index: 7
#2Partha Basu (IARC: International Agency for Research on Cancer)H-Index: 19
Last.Arnie Purushotham ('KCL': King's College London)H-Index: 34
view all 24 authors...
Summary Efforts are being made to scale up human papillomavirus (HPV) vaccination for adolescent girls in India. Bivalent and quadrivalent HPV vaccines were licensed in the country in 2008, and a nonavalent vaccine was licensed in 2018. Demonstration projects initiated in Andhra Pradesh and Gujarat in 2009 introduced HPV vaccination in public health services in India. Following a few deaths in these projects, although subsequently deemed unrelated to vaccination, HPV vaccination in research proj...
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