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Angela Dispenzieri
Mayo Clinic
1,213Publications
96H-index
37.9kCitations
Publications 1213
Newest
Published in Leukemia 9.94
Kristine Misund12
Estimated H-index: 12
(NTNU: Norwegian University of Science and Technology),
Niamh Keane2
Estimated H-index: 2
(National University of Ireland, Galway)
+ -3 AuthorsEsteban Braggio29
Estimated H-index: 29
(Mayo Clinic)
Published in Journal of Cardiac Failure 3.86
Michael Polydefkis30
Estimated H-index: 30
(Johns Hopkins University),
Julian D. Gillmore47
Estimated H-index: 47
+ -3 AuthorsArnt V. Kristen27
Estimated H-index: 27
(Heidelberg University)
Hereditary transthyretin-mediated (hATTR) amyloidosis is a rapidly progressive, fatal disease caused by transthyretin gene mutations resulting in amyloid deposition in multiple organs and tissues. Heterogenous clinical manifestations occur and most patients (pts) develop a mixed phenotype of polyneuropathy and cardiomyopathy. Patisiran, an RNAi therapeutic, was investigated in APOLLO (NCT01960348), the largest study in pts with hATTR amyloidosis with polyneuropathy; 56% of pts qualified for the ...
Published on Apr 1, 2019in American Journal of Kidney Diseases 6.65
Samih H. Nasr45
Estimated H-index: 45
(Mayo Clinic),
Christophe Sirac14
Estimated H-index: 14
(University of Limoges)
+ 13 AuthorsMariam P. Alexander11
Estimated H-index: 11
(Mayo Clinic)
Heavy chain amyloidosis and heavy chain deposition disease are the only known kidney diseases caused by the deposition of truncated immunoglobulin heavy chains. Fibrillary glomerulonephritis typically results from deposition of DNAJB9 (DnaJ heat shock protein family [Hsp40] member B9) and polytypic immunoglobulin G (IgG). We describe a patient with monoclonal gammopathy (IgG with λ light chain) who developed DNAJB9-negative fibrillary glomerulonephritis leading to end-stage kidney disease, with ...
Published on May 1, 2019in Biology of Blood and Marrow Transplantation 3.60
Abdullah S. Al Saleh , M. Hasib Sidiqi2
Estimated H-index: 2
+ 12 AuthorsWilson I. Gonsalves19
Estimated H-index: 19
Abstract Prior reports have suggested that 3 or more organs involved is a contraindication for autologous stem cell transplant (ASCT) in amyloid light chain (AL) amyloidosis. Therefore, most centers limit transplantation to patients who have no more than 2 organs significantly involved. We retrospectively reviewed all patients with AL amyloidosis with ≥3 involved organs and who had ASCT between 1996 and 2015 at Mayo Clinic, Rochester, Minnesota to assess transplant safety and outcomes. Seventy-f...
Published on Jun 1, 2019in Journal of The American Society of Echocardiography 6.11
Cristina D Pislaru23
Estimated H-index: 23
(Mayo Clinic),
Filip Ionescu (Mayo Clinic)+ 5 AuthorsSorin V. Pislaru21
Estimated H-index: 21
(Mayo Clinic)
Background The aim of this study was to test the hypothesis that intrinsic cardiac elastography can detect diastolic tissue abnormalities produced by cardiac amyloid infiltration and that measurements may have incremental value beyond traditional echocardiographic measures. The specific aims were (1) to evaluate the relationship between left ventricular myocardial stiffness (by elastography) and measures of diastolic chamber stiffness and systolic strain in patients with amyloidosis and (2) to c...
Published in Journal of Cardiac Failure 3.86
Daniel P. Judge29
Estimated H-index: 29
(MUSC: Medical University of South Carolina),
Alejandra González-Duarte5
Estimated H-index: 5
+ -3 AuthorsMichael Polydefkis30
Estimated H-index: 30
(Johns Hopkins University)
Hereditary transthyretin-mediated (hATTR) amyloidosis is a rapidly progressive, multisystem disease which can impact numerous organs, including peripheral and autonomic nerves and heart. Orthostatic intolerance (OI), caused by amyloid deposition in the autonomic nervous system, is commonly reported in patients with hATTR amyloidosis. OI increases the risk that patients will experience clinically significant events, such as presyncope, syncope, and falls. In the Phase 3 APOLLO study, patisiran de...
Published on Jan 1, 2019in Clinical Chemistry 6.89
Lusia Sepiashvili5
Estimated H-index: 5
(U of T: University of Toronto),
Mindy Kohlhagen4
Estimated H-index: 4
(Mayo Clinic)
+ 4 AuthorsDavid L. Murray19
Estimated H-index: 19
(Mayo Clinic)
Background: Free light chain (FLC) quantification is the most analytically sensitive blood-based method commercially available to diagnose and monitor patients with plasma cell disorders (PCDs). However, instead of directly detecting monoclonal FLCs (mFLCs), FLC assays indirectly assess clonality based on quantifying κ and λ FLCs and determination of the к/λ FLC ratio. Often an abnormal FLC ratio is the only indication of a PCD, and confirmation by a direct method increases diagnostic confidence...
Published on Jul 4, 2019in American Journal of Hematology 6.14
Abdullah S. Al Saleh (King Saud bin Abdulaziz University for Health Sciences), M. Hasib Sidiqi2
Estimated H-index: 2
(Mayo Clinic)
+ 14 AuthorsTaxiarchis Kourelis18
Estimated H-index: 18
(Mayo Clinic)
Published on Jul 17, 2019in American Journal of Hematology 6.14
Jennifer Yui3
Estimated H-index: 3
(Mayo Clinic),
Daniel Garceau + 7 AuthorsNelson Leung51
Estimated H-index: 51
(Mayo Clinic)
Published on Jul 12, 2019in British Journal of Haematology 5.21
Eli Muchtar10
Estimated H-index: 10
(Mayo Clinic),
Morie A. Gertz100
Estimated H-index: 100
(Mayo Clinic)
+ 22 AuthorsPrashant Kapoor27
Estimated H-index: 27
(Mayo Clinic)
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