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Prak Sophonneary
Ministry of Health (Cambodia)
17Publications
8H-index
106Citations
Publications 17
Newest
#1Kyly C. Whitfield (Mount Saint Vincent University)H-Index: 8
#2Hou Kroeun (Helen Keller International)H-Index: 10
Last.Jelisa Gallant (Mount Saint Vincent University)
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Introduction Thiamine (vitamin B1) deficiency remains a concern in Cambodia where women with low thiamine intake produce thiamine-poor milk, putting their breastfed infants at risk of impaired cognitive development and potentially fatal infantile beriberi. Thiamine fortification of salt is a potentially low-cost, passive means of combating thiamine deficiency; however, both the dose of thiamine required to optimise milk thiamine concentrations as well as usual salt intake of lactating women are ...
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#1Alejandra M. Wiedeman (UBC: University of British Columbia)H-Index: 2
#2Kyly C. Whitfield (UBC: University of British Columbia)H-Index: 8
Last.Susan I. Barr (UBC: University of British Columbia)H-Index: 3
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Choline has critical roles during periods of rapid growth and development, such as infancy. In human milk, choline is mostly present in water-soluble forms (free choline, phosphocholine, and glycerophosphocholine). It is thought that milk choline concentration is influenced by maternal choline intake, and the richest food sources for choline are of animal origin. Scarce information exists on milk choline from countries differing in animal-source food availability. In this secondary analysis of s...
2 CitationsSource
#1Kyly C. Whitfield (Mount Saint Vincent University)H-Index: 8
#2Geoffry Smith (International Life Sciences Institute)H-Index: 4
Last.Frank Tammo Wieringa (SupAgro)H-Index: 3
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Background Thiamine deficiency is thought to be an issue in Cambodia and throughout Southeast Asia due to frequent clinical reports of infantile beriberi. However the extent of this public health issue is currently unknown due to a lack of population-representative data. Therefore we assessed the thiamine status (measured as erythrocyte thiamine diphosphate concentrations; eThDP) among a representative sample of Cambodian women of childbearing age (15–49 y) and their young children (6–69 mo). Me...
11 CitationsSource
#1Adrian McCannH-Index: 8
#2Øivind MidttunH-Index: 32
Last.Timothy J. GreenH-Index: 34
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Background: Traditionally, vitamin B1 status is assessed by a functional test measuring erythrocyte transketolase (ETK) activity or direct measurement of erythrocyte thiamine diphosphate (eThDP) concentration. However, such analyses are logistically challenging, and do not allow assessment of vitamin B1 status in plasma/serum samples stored in biobanks. Using a multiplex assay, we evaluated plasma concentrations of thiamine and thiamine monophosphate (TMP), as alternative, convenient measures of...
3 CitationsSource
#1Philip Chebaya (UBC: University of British Columbia)H-Index: 1
#2Crystal D. Karakochuk (UBC: University of British Columbia)H-Index: 9
Last.Kyly C. Whitfield (UBC: University of British Columbia)H-Index: 8
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Vitamin B12 plays an essential role in fetal and infant development. In regions where animal source food consumption is low and perinatal supplementation is uncommon, infants are at risk of vitamin B12 deficiency. In this secondary analysis, we measured total vitamin B12 concentrations in maternal and infant serum/plasma and breast milk among two samples of mother–infant dyads in Canada (assessed at 8 weeks post-partum) and in Cambodia (assessed between 3–27 weeks post-partum). Canadian mothers ...
8 CitationsSource
#1Kyly C. Whitfield (UBC: University of British Columbia)H-Index: 8
#2Crystal D. Karakochuk (UBC: University of British Columbia)H-Index: 9
Last.Timothy J. Green (University of Adelaide)H-Index: 34
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Objectives To assess whether ad libitum consumption of thiamin-fortified fish sauce over 6 months yields higher erythrocyte thiamin diphosphate concentrations (eTDP) among women of childbearing age and their children aged 12-59 months compared with control sauce containing no thiamin. Study design In this double-blind, randomized controlled efficacy trial, 276 nonpregnant, nonlactating women (18-45 years of age) and their families in Prey Veng, Cambodia, were randomized to receive 1 of 3 fish sa...
8 CitationsSource
#1Kyly C. Whitfield (UBC: University of British Columbia)H-Index: 8
#2Crystal D. Karakochuk (UBC: University of British Columbia)H-Index: 9
Last.Timothy J. Green (University of Adelaide)H-Index: 34
view all 15 authors...
Importance Infantile beriberi, a potentially fatal disease caused by thiamine deficiency, remains a public health concern in Cambodia and regions where thiamine-poor white rice is a staple food. Low maternal thiamine intake reduces breast milk thiamine concentrations, placing breastfed infants at risk of beriberi. Objective To determine if consumption of thiamine-fortified fish sauce yields higher erythrocyte thiamine diphosphate concentrations (eTDP) among lactating women and newborn infants an...
15 CitationsSource
#2Prak SophonnearyH-Index: 8
Last.Jacques BergerH-Index: 22
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We would like to submit the following as a correction to our recently published paper [1] because of the use of the wrong cut-off for overweight.[...]
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#2Prak Sophonneary (IRD: Institut de recherche pour le développement)H-Index: 8
Last.Jacques Berger (IRD: Institut de recherche pour le développement)H-Index: 22
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The study assessed the trends of nutritional status of children under age five in Cambodia over four DHS surveys from 2000 to 2014 and the contribution of socioeconomic and demographic factors to its changes. Undernutrition was a public health problem in all surveys. Despite consistent improvement over the years, stunting still affected 32.5% of children in 2014. Wasting prevalence did not improve since 2005 and affected 9.6% of children under five in 2014. Low wealth and mother education; and r...
10 CitationsSource
#1Geoffry SmithH-Index: 4
Last.Frank T. WieringaH-Index: 18
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Recent studies have shown that in spite of being generally close to the equator; vitamin D deficiency is common in South East Asian countries. In order to quantify micronutrient status for women and children in Cambodia; a nationally-representative survey was conducted in 2014 linked to the Cambodian Demographic Health Survey. The countrywide median of 25(OH)D was, respectively, 64.9 and 91.1 nmol/L for mothers and children. Based on The Endocrine Society cutoffs (>50<75 nmol/L = insufficiency; ...
10 CitationsSource
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