Bronwyn A. Kingwell
Monash University
Publications 344
#1Megan S. GraceH-Index: 18
#2Melissa F. FormosaH-Index: 15
Last.Bronwyn A. KingwellH-Index: 67
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Active breaks in prolonged sitting has beneficial impacts on cardiometabolic risk biomarkers. The molecular mechanisms include regulation of skeletal muscle gene and protein expression controlling metabolic, inflammatory and cell development pathways. An active communication network exists between adipose and muscle tissue, but the effect of active breaks in prolonged sitting on adipose tissue have not been investigated. This study characterized the acute transcriptional events induced in adipos...
#1William ChanH-Index: 13
#2Bronwyn A. Kingwell (Baker IDI Heart and Diabetes Institute)H-Index: 67
Last.Stephen J. Duffy (Baker IDI Heart and Diabetes Institute)H-Index: 38
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Abstract Objective The cause of perioperative myocardial infarction (PMI) is postulated to involve hemodynamic stress or coronary plaque destabilization. We aimed to evaluate perioperative factors in patients with peripheral artery disease (PAD) undergoing major vascular surgery to determine the likely mechanisms and predictors of PMI. Methods This was a prospective cohort study of 133 patients undergoing major vascular surgery including open abdominal aortic aneurysm (AAA) repair (n = 40) and m...
We thank Dr. Harbaoui and colleagues for their interest in our paper “Impact of Pre-Procedural Blood Pressure on Long-Term Outcomes Following Percutaneous Coronary Intervention” [(1)][1]. We agree with the authors that large-artery stiffness (measured clinically as wide pulse pressure) is a
#1Robyn N. LarsenH-Index: 9
Last.David W. DunstanH-Index: 76
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Objective: This study aimed to examine the effects on postprandial glucose and insulin responses of interrupting sitting time with brief bouts of simple resistance activities (SRAs) in adults with overweight or obesity. Methods: Participants (n = 19) were recruited for a randomized crossover trial involving the following two 6-hour conditions: (1) uninterrupted sitting or (2) sitting with 3-minute bouts of SRAs (half-squats, calf raises, gluteal contractions, and knee raises) every 30 minutes (t...
#1Tilahun Nigatu Haregu (Baker IDI Heart and Diabetes Institute)H-Index: 8
#2Shane Nanayakkara (Baker IDI Heart and Diabetes Institute)H-Index: 7
Last.David M. Kaye (Baker IDI Heart and Diabetes Institute)H-Index: 75
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Background Cardiovascular diseases (CVDs) and diabetes are two of the most important public health problems. Outcomes for patients with these disorders vary considerably, likely due to the added influence of a range of interacting clinical, metabolic, environmental, lifestyle, genetic and psychosocial risk factors associated with these diseases. The Baker Biobank study was designed to characterise these factors to inform better risk prediction, earlier diagnosis and better treatment of CVDs and ...
#1Pia Varsamis (Monash University)H-Index: 2
#2Melissa F. FormosaH-Index: 15
Last.Bronwyn A. Kingwell (Monash University)H-Index: 67
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Summary Background & aims Chronic overconsumption of sugar-sweetened beverages (SSBs) is associated with unfavourable health effects, including promotion of obesity. However, the acute effects of consuming SSBs on glucose and lipid metabolism remain to be characterized in a real-world, post-prandial context of prolonged sitting. We quantified the acute effects of between-meal SSB consumption compared with water, on glucose and lipid metabolism in habitual soft drink consumers during prolonged si...
2 CitationsSource
#1Rachel E.D. ClimieH-Index: 7
#2Bronwyn A. Kingwell (CSL Limited)H-Index: 67
Last.Gemma A. Figtree (USYD: University of Sydney)H-Index: 24
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Cardiovascular disease (CVD) poses a highly significant health and economic burden in Australia and worldwide, with the latest global burden of disease study identifying cardiovascular disease as an “expanding threat to global health” [1] . Australian cardiovascular researchers are recognised internationally for their broad expertise spanning from fundamental molecular and cellular biology, through innovative bioengineering approaches, patient-focussed clinical trials, and impactful community in...
Last.Peter J. MeikleH-Index: 49
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#1Angie S. Xiang (Monash University)H-Index: 1
#2Bronwyn A. Kingwell (Monash University)H-Index: 67
Summary Low HDL cholesterol dyslipidaemia affects about half of people with type 2 diabetes and represents a major independent risk factor for atherosclerotic cardiovascular disease. The "good cholesterol" label was coined decades ago on the basis of a presumed causal role of HDL cholesterol in atherosclerotic cardiovascular disease. However, this view has been challenged by the negative results of several studies of HDL cholesterol-raising drugs, creating a paradox for clinicians regarding the ...
Background Although acute coronary syndromes (ACS) are a major cause of morbidity and mortality, relationships with biologically active lipid species potentially associated with plaque disruption/e...