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Emiko Iwaoka
Hyogo University of Health Sciences
18Publications
8H-index
171Citations
Publications 18
Newest
#1Hisae Oku (Mukogawa Women's University)H-Index: 16
#2Emiko Iwaoka (Hyogo University of Health Sciences)H-Index: 8
Last.Kyoko Ishiguro (Mukogawa Women's University)H-Index: 24
view all 6 authors...
#1Emiko Iwaoka (Hyogo University of Health Sciences)H-Index: 8
#2Shenglan Wang (Hyogo University of Health Sciences)H-Index: 9
Last.Yi Dai (Hyogo University of Health Sciences)H-Index: 28
view all 8 authors...
Evodiae fructus (EF), a fruit of Evodia rutaecarpa Bentham, has long been used as an analgesic drug in traditional Chinese and Japanese medicine. However, the underlying molecular mechanism of its pharmacological action is unclear. Here, using calcium imaging, whole-cell patch-clamp recording, and behavioral analysis, we investigated the pharmacological action of EF and its principal compound, evodiamine, on the transient receptor potential (TRP) V1 channels. Dorsal root ganglion (DRG) neurons a...
#1Shruti Chatterjee (OPU: Osaka Prefecture University)H-Index: 7
#2M. Shamim Hasan Zahid (OPU: Osaka Prefecture University)H-Index: 5
Last.Shinji Yamasaki (OPU: Osaka Prefecture University)H-Index: 39
view all 10 authors...
A newly emerged Vibrio cholerae O1 El Tor variant strain with multidrug resistance is considered a threat to public health. Recent strategies to suppress virulence factors production instead of bacterial growth may lead to less selective pressure for the emergence of resistant strains. The use of spices and their active constituents as the inhibitory agents against cholera toxin (CT) production in V. cholerae may be an alternative approach to treat cholera. In this study, we examined the potenti...
#1Hisae Oku (Mukogawa Women's University)H-Index: 3
#2Yuko Ogawa (Mukogawa Women's University)H-Index: 5
Last.Kyoko Ishiguro (Mukogawa Women's University)H-Index: 3
view all 8 authors...
Kinka-cha (dried leaf of Camellia nitidissima) is used as a folk tea for detoxication, diuresis and antihypertension. In the present study, we evaluated the extract of kinka-cha on metabolic, vascular and oxidative stress parameters in a model of metabolic syndrome, SHR/NDmcr-cp/cp (SHR/cp) rats that manifest hypertension, obesity, glucose intolerance and hyperlipidemia. Treatment with the extract of kinka-cha alleviated the increase in blood pressure, decrease in tail blood flow and elevated se...
#1Shinji Yamasaki (OPU: Osaka Prefecture University)H-Index: 39
#2Masahiro Asakura (OPU: Osaka Prefecture University)H-Index: 18
Last.Shunji Aoki (Hyogo University of Health Sciences)H-Index: 3
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The rise in multi-drug resistant Vibrio cholerae strains is a big problem in treatment of patients suffering from severe cholera. Only a few studies have evaluated the potential of natural compounds against V. cholerae. Extracts from plants like ‘neem’, ‘guazuma’, ‘daio’, apple, hop, green tea and elephant garlic have been shown to inhibit bacterial growth or the secreted cholera toxin (CT). However, inhibiting bacterial growth like common antimicrobial agents may also impose selective pressure ...
#1Hisae Oku (Mukogawa Women's University)H-Index: 3
#2Yuko OgawaH-Index: 5
Last.Kyoko Ishiguro (Mukogawa Women's University)H-Index: 3
view all 4 authors...
Allergy-preventive activity of flower buds of Lonicera japonica THUNB. was found in the 35% EtOH extract (LJ) using an in vivo assay, The assay system uses monitoring of a decrease in blood flow (BF) in the tail vein of mice subjected to sensitization with hen-egg white lysozyme (HEL). Bioassay-guided fractionation of the 35% EtOH extract led to isolation of chlorogenic acid (1) and three known iridoid derivatives, loganin (2), secoxyloganin (3) and sweroside (4), all of which inhibited the BF d...
#1Emiko Iwaoka (Hyogo University of Health Sciences)H-Index: 8
#2Hisae Oku (Mukogawa Women's University)H-Index: 3
Last.Kyoko Ishiguro (Mukogawa Women's University)H-Index: 3
view all 4 authors...
The allergy-preventive activity of a 35% EtOH extract (IT) of flowers of Impatiens textori MIQ. was demonstrated in a continuing search for allergy-preventive substances from natural sources. The evaluation of its activity used an in vivo assay method for monitoring the blood flow decrease in the tail vein microcirculation of mice subjected to sensitization with hen-egg white lysozyme. Among the principal compounds in IT, apigenin (1), luteolin (3), and luteolin 7-glucoside (4) showed significan...
#1Emiko Iwaoka (Hyogo University of Health Sciences)H-Index: 8
#2Tomoko Mori (Tohoku University)H-Index: 6
Last.Akito Tanaka (Hyogo University of Health Sciences)H-Index: 19
view all 5 authors...
Abstract Affinity chromatography is an important strategy for target identifications. However, commercial available solid materials have limitations while selection of that is sometimes vital for the purpose. We have reported a synthetic resin with a monolithic structure in previous papers. In this paper, introduction effects of spacer to the monolithic material on identification of specific binding protein was quantitatively analyzed using benzensulfonamide as a bait, which exhibited introducti...
#1Emiko Iwaoka (Mukogawa Women's University)H-Index: 8
#2Hisae Oku (Mukogawa Women's University)H-Index: 16
Last.Kyoko Ishiguro (Mukogawa Women's University)H-Index: 24
view all 4 authors...
Allergy-preventive activity was demonstrated for the MeOH extract (HM) of the petals of Hibiscus mutabilis L. ‘versicolor’ MAKINO in a continuing search for allergy-preventive substances from natural sources, using the in vivo assay method. This assay system uses monitoring of a decrease in the blood flow at the tail vein of mice subjected to hen egg-white lysozyme (HEL) sensitization. By bioassay-directed fractionation, a new flavonol triglycoside, quercetin 3-O-[β-D-xylopyranosyl(1→2)-α-L-rham...
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