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Ismail Gögenur
University of Copenhagen
SurgeryMelatoninColorectal cancerGeneral surgeryMedicine
242Publications
28H-index
2,709Citations
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#1M. CihoricH-Index: 2
Last. M. Bay-NielsenH-Index: 19
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Background: Despite the importance of predicting adverse postoperative outcomes, functional performance status as a proxy for frailty has not been systematically evaluated in emergency abdominal surgery. Our aim was to evaluate if the Eastern Cooperative Oncology Group (ECOG) performance score was independently associated with mortality following high-risk emergency abdominal surgery, in a multicentre, retrospective, observational study of a consecutive cohort. Methods: All patients aged 18 or a...
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#1Adile Orhan (UCPH: University of Copenhagen)
Last. Ismail Gögenur (UCPH: University of Copenhagen)H-Index: 28
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IMPORTANCE: Tumour-infiltrating lymphocytes (TILs) have previously been found to influence patient prognosis in other gastrointestinal cancers, for instance in colorectal cancer. An immunosuppressive phenotype often characterizes pancreatic cancer with a low degree of immune cell infiltration. Cytotoxic CD8(+) T cell infiltration in tumours is found to be the best predictive variable for response to immune checkpoint inhibitor therapy, emphasizing the importance of investigating TILs in pancreat...
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INTRODUCTION: Previous studies have suggested that choice of anaesthesia can affect long-term outcome. In this study, the association between type of anaesthesia and outcomes in terms of survival, recurrence, post-operative complications and recovery after surgery for colorectal cancer was investigated in an Enhanced Recovery after Surgery (ERAS) setting. METHODS: This was a retrospective study including patients undergoing elective curative-intended surgery for colorectal cancer between April 2...
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#1Sarah EkeloefH-Index: 2
#2Jakob Ohm OreskovH-Index: 1
Last. Ismail GögenurH-Index: 28
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BACKGROUND: Preoperative endothelial dysfunction is a predictor of myocardial injury and major adverse cardiac events. Non-cardiac surgery is known to induce acute endothelial changes. The aim of this explorative cohort study was to assess the extent of systemic endothelial dysfunction after major emergency abdominal surgery and the potential association with postoperative myocardial injury. METHODS: Patients undergoing major emergency abdominal surgery were included in this prospective cohort s...
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#2Kristian K. Jensen (Bispebjerg Hospital)H-Index: 13
Last. Ismail GögenurH-Index: 28
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Background In a retrospective cohort study, we looked at the incidence and risk factors of developing in-hospital venous thromboembolism (VTE) after major emergency abdominal surgery and the risk factors for developing a venous thrombosis.
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Last. Ismail Gögenur (UCPH: University of Copenhagen)H-Index: 28
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Abstract Background/Objective Anastomotic leakage (AL) is one of the most severe complications following colorectal cancer surgery and is associated with increased short and long term mortality. The literature is conflicting regarding increased risk of recurrence after AL. The aim of this study was to systematically review the impact of anastomotic leakage on the risk of local or distant recurrence and overall survival, cancer specific survival, and disease-free survival. Methods A systematic re...
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