Brian W. McCrindle
Arkansas Children's Hospital
SurgeryCardiologyHeart diseaseDiabetes mellitusMedicine
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Publications 910
#1Safwat A. Aly (U of T: University of Toronto)
#2Ramiro W. Lizano Santamaria (U of T: University of Toronto)H-Index: 1
Last. Brian W. McCrindle (U of T: University of Toronto)H-Index: 90
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Abstract Background Up to 25% of children with congenital heart disease are obese, which may have negative physiologic consequences for patients with repaired tetralogy of Fallot (rTOF). Methods Patients with rTOF who underwent cardiac magnetic resonance (CMR) and cardiopulmonary exercise testing from 2007-2018 were reviewed. Complex rTOF patients were excluded. Obese patients (body mass index [BMI]≥95th%ile) were compared to normal-weight patients (BMI Results We compared 32 obese patients matc...
#1Brian W. McCrindle (U of T: University of Toronto)H-Index: 90
#2Cedric Manlhiot (JHUSOM: Johns Hopkins University School of Medicine)
#1Rae-Ellen W. Kavey (URMC: University of Rochester Medical Center)H-Index: 23
#2Cedric Manlhiot (U of T: University of Toronto)H-Index: 43
Last. Michael Khoury (Cincinnati Children's Hospital Medical Center)H-Index: 2
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Abstract Background Statin use for hypercholesterolemia in children is predominantly reported from short-term clinical trials. In this study, we assess the efficacy and safety of statin treatment in clinical pediatric practice. Methods Records of all patients who began statin treatment at 6 months from five Pediatric Lipid Clinics were reviewed. Information at baseline and from all clinic evaluations after statin initiation was recorded, including lipid measurements, statin drug/dose, safety mea...
#1Michael Khoury (U of A: University of Alberta)
#2Angie Mae Rodday (Tufts University)H-Index: 18
Last. Sarah D. de Ferranti (Boston Children's Hospital)H-Index: 42
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Abstract The pediatric lipid screening and treatment practices, attitudes, and perceived barriers of Canadian pediatricians are not known. We sought to evaluate this in a survey of pediatricians through the Canadian Pediatric Surveillance Program (CPSP) in March 2019. The survey included an assessment of lipid screening of 9-11 year-old youth and a hypothetical case of persistent severe dyslipidemia to ascertain management practices. There were 759 respondents (28% response rate, 759/2,742), of ...
#1Linda M. Lambert (Primary Children's Hospital)H-Index: 23
#2Brian W. McCrindleH-Index: 90
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Abstract Background Growth abnormalities in single ventricle survivors may reduce quality of life (QoL) and exercise capacity. Methods This multicenter, longitudinal analysis evaluated changes in height and body mass index (BMI) compared to population norms and their relationship to mortality, ventricular morphology, QoL, and exercise capacity in the Pediatric Heart Network (PHN) Fontan studies. Results Fontan1 (F1) included 546 participants (12 ± 3.4 yrs.), Fontan 2 (F2) 427 (19 ± 3.4 yrs.), an...
#1Sara DiLauro (U of T: University of Toronto)H-Index: 1
#2Jennifer L. Russell (U of T: University of Toronto)H-Index: 15
Last. Deborah L O'ConnorH-Index: 31
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Summary Background & aim Previously we showed that modified fat breast milk (MFBM) facilitated resolution of post-surgical chylothorax in cardiac infants, but their weight-for-age and length-for-age z-scores declined over the ≥6-week treatment duration. Our aim was to evaluate the growth of infants diagnosed with post-surgical chylothorax and fed according to one of two proactive feeding protocols using MFBM or a high medium triglyceride (MCT)-containing formula (standard of care). Methods In th...
#1Ashraf S. Harahsheh (GW: George Washington University)H-Index: 5
#2Nagib Dahdah (UdeM: Université de Montréal)H-Index: 18
Last. Dongngan T. Truong (Primary Children's Hospital)H-Index: 5
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6 CitationsSource
#1Benedetta LeonardiH-Index: 8
#2Fabrizio DragoH-Index: 24
Last. Gerald LebovicH-Index: 15
view all 21 authors...
Although cardiovascular magnetic resonance (CMR) imaging measurements are known to differ between sexes and according to age in the normal heart, little is known about measurement variability in patients with congenital heart disease (CHD). Yet, aggregate CMR data, without adjustment for sex or age
#1Anusha Jegatheeswaran (U of T: University of Toronto)H-Index: 10
#2Paul J. Devlin (U of T: University of Toronto)H-Index: 4
Last. Carlos M. Mery (University of Texas at Austin)H-Index: 12
view all 14 authors...
Structured abstract Objectives It remains unclear when sudden cardiac event risk outweighs surgical risk for anomalous aortic origin of a coronary artery (AAOCA) patients. The Congenital Heart Surgeons' Society sought to characterize the surgical risks by determining the techniques, complications, and outcomes of repair. Methods Between 01/2000-09/2018, 682 AAOCA patients age ≤30 years (y) were enrolled. Demographic, morphologic, operative, imaging, and ischemia-related data were analyzed. Resul...
2 CitationsSource