Qiang Zhao
Georgia State University
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Publications 2
#1Qiang Zhao (GSU: Georgia State University)H-Index: 1
#2Kathleen A Coughlan (Redlands Community College)H-Index: 1
Last. Ping Song (GSU: Georgia State University)H-Index: 1
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Recent evidence indicates that activation of adenosine monophosphate-activated protein kinase (AMPK), a highly conserved sensor and modulator of cellular energy and redox, regulates cell mitosis. However, the underlying molecular mechanisms for AMPKα subunit regulation of chromosome segregation remain poorly understood. This study aimed to ascertain if AMPKα1 deletion contributes to chromosome missegregation by elevating Polo-like kinase 4 (PLK4) expression. Centrosome proteins and aneuploidy we...
1 CitationsSource
#1Ping Song (GSU: Georgia State University)H-Index: 1
#2Qiang Zhao (GSU: Georgia State University)H-Index: 1
Last. Ming-Hui Zou (GSU: Georgia State University)H-Index: 45
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Abstract Cardiovascular disease (CVD) is the most common disease to increase as life expectancy increases. Most high-profile pharmacological treatments for age-related CVD have led to inefficacious results, implying that novel approaches to treating these pathologies are needed. Emerging data have demonstrated that senescent cardiovascular cells, which are characterized by irreversible cell cycle arrest and a distinct senescence-associated secretory phenotype, accumulate in aged or diseased card...
1 CitationsSource