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Kevin Kee Hoe Cheah
University of Malaya
Intrinsic apoptosisApoptosisG1 phaseTriazoleCell cycleCancer researchBiochemistryCell growthCancer cell
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#1Stephanie Bernardine (UM: University of Malaya)
#2Kok Hoong Leong (UM: University of Malaya)H-Index: 10
Last. Kevin Kee Hoe Cheah (UM: University of Malaya)
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BACKGROUND: Oxadiazoles, triazoles, and their respective precursors have been shown to exhibit various pharmacological properties, namely antitumour activities. Cytotoxic activity was reported for these compounds in various cancer cell lines. AIM AND OBJECTIVES: In this study, we aim at investigating the mechanism of apoptosis by N-(4-chlorophenyl)-2-(4-(3,4,5-trimethoxybenzyloxy)benzoyl)-hydrazinecarbothioami de, a triazole precursor, henceforth termed compound P7a, in breast cancer cell line, ...
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