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James M Chamberlain
Randomized controlled trialIntention-to-treat analysisFosphenytoinLevetiracetamStatus epilepticus
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#2Jaideep Kapur (UVA: University of Virginia)H-Index: 36
Last. Daniel H. Lowenstein (UCSF: University of California, San Francisco)H-Index: 70
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Summary Background Benzodiazepine-refractory, or established, status epilepticus is thought to be of similar pathophysiology in children and adults, but differences in underlying aetiology and pharmacodynamics might differentially affect response to therapy. In the Established Status Epilepticus Treatment Trial (ESETT) we compared the efficacy and safety of levetiracetam, fosphenytoin, and valproate in established status epilepticus, and here we describe our results after extending enrolment in ...
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