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R. J. Nija
Amrita Institute of Medical Sciences and Research Centre
AnatomyInnate immune systemSepsisBlood cellStem cellExtracellularLiterature surveyBiologyImmune systemCell biology
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Extracellular trap formation (ETosis) by various blood cells has been reported. This trap contains DNA, histones and granular proteins which can elicit an innate immune response by entrapping microorganisms. The trap thus formed has been reported to have an involvement in various pathogenic conditions as well. This review focusses on the trap formation by different blood cells, the immune response associated with trap formation and also its role in various clinical conditions. An extensive liter...
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