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Phan Van Kiem
Vietnam Academy of Science and Technology
297Publications
21H-index
1,809Citations
Publications 307
Newest
#2Nguyen Bich Thu (Duy Tan University)H-Index: 3
Last.Seung Hyun Kim (Yonsei University)H-Index: 26
view all 12 authors...
Abstract Six undescribed sesquiterpene glucosides, fissispallins A-F, and one known sesquiterpene glucoside, fissispallin, were discovered in the leaves of Fissistigma pallens (Finet & Gagnep.) Merr. The structures were determined using spectroscopic methods, including 1D, 2D NMR, and MS. All compounds were evaluated for cytotoxic activity against three human cancer cell lines, HT-29, A-2058, and A-549. Fissispallin A showed potent activity with the IC50 values less than 1.5 μM against all teste...
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#1Nguyen Thi MaiH-Index: 3
#2Duong Thi Dung (VAST: Vietnam Academy of Science and Technology)H-Index: 2
Last.Yohan Seo (Yonsei University)H-Index: 4
view all 13 authors...
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#1Nguyen Thi MaiH-Index: 3
#2Vu Van Doan (VAST: Vietnam Academy of Science and Technology)
Last.Phan Van Kiem (VAST: Vietnam Academy of Science and Technology)H-Index: 21
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AbstractExtensive phytochemical investigation of Schisandra sphenanthera leaves resulted in the isolation of six highly oxygenated nortriterpenoids (1–6) and five lignans (7–11) including a new pre...
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#1Pham Hai Yen (VAST: Vietnam Academy of Science and Technology)H-Index: 10
#2Vu Van Doan (VAST: Vietnam Academy of Science and Technology)
Last.Phan Van Kiem (VAST: Vietnam Academy of Science and Technology)H-Index: 21
view all 11 authors...
AbstractThree new triterpene saponins including two lupane-types and an ursane-type were isolated from the leaves of Trevesia palmata. Their structures were determined as 2α,3β,23-trihydroxylup-20(...
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#1Nguyen Xuan Nhiem (VAST: Vietnam Academy of Science and Technology)H-Index: 14
Last.Seung Hyun Kim (Yonsei University)H-Index: 26
view all 10 authors...
ABSTRACTThree new flavonol glycosides, fissflavosides A-C (1–3), together with six known flavonol glycosides, kaempferol 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-galactopyranoside (4), kaempferol 3-O-α-L-...
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#1Tran Hong Quang (VAST: Vietnam Academy of Science and Technology)H-Index: 12
#2Duong Thi Hai Yen (VAST: Vietnam Academy of Science and Technology)H-Index: 2
Last.Chau Van Minh (VAST: Vietnam Academy of Science and Technology)H-Index: 23
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Abstract Polygala aureocauda Dunn. (Polygalaceae) has been widely used in Vietnamese traditional medicine for the treatment of hepatitis, nephritis, sonasthenia, anaemia, back pain, and knee fatigue. Chemical investigation of a methanol extract of P. aureocauda roots resulted in the isolation of four new oleanane triterpenoid saponins (polyaureosides A–D) and two known ones (polygalasaponin XLVIII and arilloside A). Their structures were elucidated by comprehensive spectroscopic methods, includi...
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#1Doan Thi Mai Huonga (VAST: Vietnam Academy of Science and Technology)
#2Le Tran Nguyen Vu (VAST: Vietnam Academy of Science and Technology)
Last.Van Cuong Pham (VAST: Vietnam Academy of Science and Technology)H-Index: 12
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Abstract Three new prenylated flavonoids, macarindicins D–F (1-3) together with eight known compounds, macadenathin B (4), glyasperin A (5), kaempferol (6), quercetin (7), quercitrin (8), (+)-isolariciresinol (9), (–)-woonenoside XI (10), and (+)-lyoniresinol 4-O-β- d- glucopyranoside (11) were isolated from the leaves of Macaranga indica Wight. Their structures were determined on the basis of extensive spectroscopic methods, including 1D-, 2D-NMR and MS data. All the isolated compounds were eva...
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#2Chu Van MenH-Index: 2
Last.Phan Van Kiem (VAST: Vietnam Academy of Science and Technology)H-Index: 21
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AbstractTwo new flavonol glycosides, fissmacosides A (1) and B (2) along with two known flavonol glycosides, kaempferol 3-O-α-l-rhamnopyranosyl-(1→6)-β-d-galactopyranoside (3) and kaempferol 3-O-β-...
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#1N. T. Ngoc (VAST: Vietnam Academy of Science and Technology)
#2Tran Thi Hong Hanh (VAST: Vietnam Academy of Science and Technology)H-Index: 8
Last.Chau V. Minh (VAST: Vietnam Academy of Science and Technology)H-Index: 5
view all 10 authors...
Four pregnane-type steroids including the new compound 5-α-pregn-20-en-3,6-dione (1) and two known cholestane-type steroids were isolated from the MeOH extract of the octocoral Dendronephthya mucronata. The structures of the compounds were elucidated using spectral data (PMR and 13C NMR, HSQC, HMBC, 1H−1H COSY, NOESY, HR-QTOF-MS) and comparisons with previously published information. The steroids exhibited moderate or weak inhibitory effects on inflammatory lipopolysaccharide-induced NO formatio...
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#1Nguyen Dinh Luyen (VAST: Vietnam Academy of Science and Technology)H-Index: 1
#2Le Mai Huong (VAST: Vietnam Academy of Science and Technology)H-Index: 7
Last.Phan Van KiemH-Index: 21
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Chemical investigation of the Kappaphycus alvarezii-derived endophytic fungus Aspergillus micronesiensis lead to the isolation of three novel dibenzospiroketals, aspermicrones A-C (1-3). Their chemical structures were determined by extensive analysis of HR-ESI-MS and NMR spectral data. The absolute configurations of them were determined by experimental and TD-DFT theoretical calculated circular dichroism spectra. Compound 2 exhibited selective cytotoxic effect toward HepG2 cell line (IC50 = 9.9 ...
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