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Saritha Shetty
ElectrospinningNanotechnologyOrganic chemistryChemistryQuality by DesignBiocompatibilityDrug deliveryCritical quality attributesChemical engineeringPolymerNanofiber
2Publications
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Abstract Nanofibers have unique potentials in tissue engineering, medical devices, drug delivery, diagnostics etc. due to their exceptional properties like high porosity, large surface area to volume ratio, functionality flexibility, good mechanical strength etc. Nanofibers prepared by electrospinning has grabbed the attention of many recently due to the flexibility and tailoring properties of biopolymers. Various manufacturing variables that affect the morphology of nanofibers and other process...
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#1Govind SoniH-Index: 4
#2Ketaki KaleH-Index: 1
Last. Khushwant S. YadavH-Index: 10
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Abstract Polymeric nanoparticles prepared using high pressure homogenizer (HPH) present some unique challenges during manufacturing which can be better understood by application of quality by design (QbD) approaches. The present review highlights the ways to identify the critical material attributes which includes the anticancer drugs, polymers, surfactants, solvent system and dispersion system. A comprehensive understanding of the critical processing parameters like pressure and number of cycle...
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