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A. García
Single-nucleotide polymorphismType 2 diabetesInsulin resistanceCholesterolDiabetes mellitus
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#2Hortensia Moreno-Macías (UAM: Universidad Autónoma Metropolitana)H-Index: 19
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Type 2 diabetes (T2D) and low serum concentration of high-density lipoprotein cholesterol (HDL-c) are common coexisting metabolic disorders. ABCA1 variants have been shown to be associated to these conditions. We sought to test the combined effect of two ABCA1 gene common variants, rs2422493 (− 565C > T) and rs9282541 (R230C) on HDL-c levels and T2D risk. Path analysis was conducted in 3,303 Mexican-mestizos to assess the specific contributions of rs2422493 and rs9282541 ABCA1 variants, insulin ...
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