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Kevin M.-C. Lee
University of Melbourne
OsteoarthritisBlockadeDiseaseSynovitisRegimen
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#1Kevin M.-C. Lee (University of Melbourne)
#2Varun Prasad (University of Melbourne)
Last. Andrew D. Cook (University of Melbourne)H-Index: 32
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Summary OBJECTIVES Pharmacological options for treating osteoarthritis (OA) are limited and alternative treatments are required. Given the clinical data indicating that granulocyte macrophage-colony stimulating factor (GM-CSF) may be a therapeutic target in human OA, we evaluated different treatment regimens with a neutralizing anti-GM-CSF monoclonal antibody (mAb) in an experimental OA model to determine their effectiveness on amelioration of pain and disease. METHODS The collagenase-induced os...
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