Match!
Wei Jiang
Chinese Academy of Sciences
InsertionSomatic hypermutationChinese hamster ovary cellActivation-induced (cytidine) deaminaseCytidine deaminaseCell CloneRecombinase-mediated cassette exchangeMutationBiology
2Publications
0Citations
What is this?
Publications 2
Newest
#1Yingjun FanH-Index: 1
Last. Haiying HangH-Index: 20
view all 6 authors...
Source
#1Yingjun Fan (CAS: Chinese Academy of Sciences)H-Index: 1
#2Wei Jiang (CAS: Chinese Academy of Sciences)
Last. Haiying Hang (CAS: Chinese Academy of Sciences)H-Index: 20
view all 6 authors...
Antibodies have been extensively used for the purpose of scientific research, clinical diagnosis, and therapy. Combination of in vitro somatic hypermutation and mammalian cell surface display has been an efficient technology for antibody or other proteins optimization, in which the efficiency of activation-induced cytidine deaminase (AID) mutations in genes is one of the most important key factors. Gene transcriptional level has been found to be positively proportional to AID-induced mutation fr...
Source
1
Close Researchers