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Nicolai P. Ostberg
Yale University
DissectionDegenerative diseaseDiseaseAortaThoracic aortic aneurysm
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#1Nicolai P. OstbergH-Index: 1
#2Mohammad A. ZafarH-Index: 6
Last. John A. Elefteriades (Yale University)H-Index: 55
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Thoracic aortic aneurysm and dissection (TAAD) affects many patients globally and has high mortality rates if undetected. Once thought to be solely a degenerative disease that afflicted the aorta due to high pressure and biomechanical stress, extensive investigation of the heritability and natural history of TAAD has shown a clear genetic basis for the disease. Here, we review both the cellular mechanisms and clinical manifestations of syndromic and non-syndromic TAAD. We particularly focus on g...
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