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Vivian van Heekeren
University of York
ProteomeGeologyPaleontologyArchaeologyDeamidationShotgunComputational biology
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#1Abigail Ramsøe (Ebor: University of York)H-Index: 1
#2Vivian van Heekeren (Ebor: University of York)
Last. Matthew J. Collins (McDonald Institute for Archaeological Research)H-Index: 54
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Abstract Contamination is a potential problem in the study of ancient proteins, either from prior handling of the sample, laboratory consumables, or cross-sample carryover from mass spectrometers. Recently, deamidation of glutamine has been proposed as a measure for assessing the degradation of ancient proteins. Here, we present deamiDATE 1.0, a method for the authentication of ancient proteins using measure of site-specific deamidation rates. We test this approach on shotgun proteomic data deri...
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