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Stephanie Ka Ching Lau
University of Ottawa
AllergyAsthmaAtopic dermatitisDupilumabIgG4-related disease
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#1Rachel SimpsonH-Index: 1
#2Stephanie Ka Ching Lau (U of O: University of Ottawa)H-Index: 1
Last. Jason Kihyuk LeeH-Index: 1
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IgG4-related disease (IgG4-RD) is a rare fibroinflammatory, multisystemic condition with a relapsing-remitting progression.1 The level of serum IgG4 correlates with inflammatory activity and organ involvement.1 Glucocorticoids are first line for IgG4-RD, but there are numerous adverse effects with chronic use.2 Dupilumab is a monoclonal antibody that acts on the interleukin 4 (IL-4) receptor alpha, shared by the IL-4 and IL-13 receptors.1 IL-4 causes isotype switching from IgM to IgG4 and IL-13 ...
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