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Stefania Gorini
Mineralocorticoid receptorArterial stiffnessAldosteroneVasoconstrictionBlood pressure
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#1Stefania GoriniH-Index: 8
Last. Massimiliano Caprio (OU: Open University)H-Index: 25
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The mineralocorticoid receptor (MR) was originally identified as a regulator of blood pressure, able to modulate renal sodium handling in response to its principal ligand aldosterone. MR is also expressed in many tissues other than kidney, including the heart, vasculature and adipose tissue. More recent studies have shown that extra-renal MR plays a relevant role in the control of cardiovascular and metabolic functions and has recently been implicated in the pathophysiology of aging. MR activati...
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