Daniel H. Schanne
University of Zurich
Systemic therapyLung cancerMetastasisDiseaseMEDLINEPrimary tumorRadiation therapyClinical trialMedicine
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Publications 3
#1Matthias Guckenberger (UZH: University of Zurich)H-Index: 51
#2Yolande Lievens (Ghent University Hospital)H-Index: 19
Last. Piet Ost (Ghent University Hospital)H-Index: 31
view all 20 authors...
Summary Oligometastatic disease has been proposed as an intermediate state between localised and systemically metastasised disease. In the absence of randomised phase 3 trials, early clinical studies show improved survival when radical local therapy is added to standard systemic therapy for oligometastatic disease. However, since no biomarker for the identification of patients with true oligometastatic disease is clinically available, the diagnosis of oligometastatic disease is based solely on i...
15 CitationsSource
#1Michael Mayinger (UZH: University of Zurich)H-Index: 2
#2Johannes Kraft (UZH: University of Zurich)H-Index: 3
Last. Nicolaus Andratschke (UZH: University of Zurich)H-Index: 23
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Abstract Purpose Neurocognitive changes are well described after prophylactic or therapeutic whole-brain radiotherapy (WBRT) and have been reported as early as 3 months after radiotherapy (RT). Therefore, WBRT with protection of the hippocampal region (hippocampal avoidance, HA) has been proposed to preserve neurocognition. Our aim was to compare the risk of leukoencephalopathy after prophylactic cranial irradiation (PCI) with or without HA. Methods Patients with small-cell lung cancer who recei...
3 CitationsSource
#1Daniel H. Schanne (UZH: University of Zurich)H-Index: 3
#2Jana Heitmann (UZH: University of Zurich)H-Index: 3
Last. Nicolaus Andratschke (UZH: University of Zurich)H-Index: 23
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Abstract Background The concept of oligometastatic disease (OMD) has expanded the scope of potentially curative therapy for metastatic NSCLC. However, large uncertainties remain regarding its definition and optimal management strategies. We therefore conducted a systematic review to investigate the value of various multimodality treatment concepts. Methods We searched the available literature in Pubmed, Medline and EMBASE using the terms “oligomet*”, “synchron*”, “oligorec*”, “metachr*” “NSCLC”,...
5 CitationsSource