Yu-Shan Cheng
National Institutes of Health
Publications 1
#1Yu-Shan Cheng (NIH: National Institutes of Health)
#2Peter R. Williamson (NIH: National Institutes of Health)H-Index: 36
Last.Wei Zheng (NIH: National Institutes of Health)H-Index: 110
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Infections from multidrug resistant (MDR) pathogens and emerging viruses present challenges for effective clinical treatments. Drug repurposing and combination screens may provide therapies at a fraction of the time and cost of traditional methods of drug development. Synergistic combinations of two or three known compounds can increase therapeutic efficacy and reduce concentrations required for individual drugs, in turn, reducing the risk of drug toxicity. Using libraries of approved drugs, tra...