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Ankit Awasthi
Lovely Professional University
Colloidal goldEndocrinologyIntensive care medicineBioavailabilityChemistryDiabetes managementDrug deliveryDrugDiabetes mellitusPharmacology
7Publications
1H-index
2Citations
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Publications 11
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#1Dipanjoy Ghosh (LPU: Lovely Professional University)H-Index: 1
#2Sachin Kumar Singh (LPU: Lovely Professional University)H-Index: 10
Last. Ankit Awasthi (LPU: Lovely Professional University)H-Index: 1
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AbstractDevelopment of self-nanoemulsifying drug delivery systems (SNEDDS) of docosahexaenoic acid (DHA) is reported with the aim to achieve enhanced dissolution rate. The optimized composition of ...
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#1Yogita Kumari (LPU: Lovely Professional University)H-Index: 4
#2Sachin Kumar Singh (LPU: Lovely Professional University)H-Index: 10
Last. Clarisse Ayinkamiye (LPU: Lovely Professional University)
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Abstract The study entailed formulation of gold nanoparticles (AuNPs) upon reduction of chloroauric acid by modified apple polysaccharide (MAP). AuNPs were conjugated with insulin (INS) for its oral delivery to treat type 1 diabetes mellitus (DM). The size of MAP conjugated AuNPs loaded with INS was 124 ± 8.55 nm with zeta potential −10.5 ± 0.54 mV. The animal study carried out in streptozotocin induced rat model revealed that AuNPs conjugated insulin (AuNPs-INS) in high dose caused 3.36 folds d...
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#1Arya Kadukkattil Ramanunny (LPU: Lovely Professional University)H-Index: 1
#2Sheetu Wadhwa (LPU: Lovely Professional University)H-Index: 10
Last. Ankit Awasthi (LPU: Lovely Professional University)H-Index: 1
view all 6 authors...
BACKGROUND: Psoriasis is a genetically predisposed autoimmune disease mediated by cytokines released by the activated immune cells. It manifests inflammatory, scaly red or white silvery flaky skin which may be a fluid-filled lesion with soreness and itchiness. The prevalence rate of psoriasis is increasing day by day. Despite having such a high prevalence rate, the treatment of psoriasis is still limited. Hence, there is a need to rethink the various treatment strategies available in the allopat...
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#1Rubiya Khursheed (LPU: Lovely Professional University)H-Index: 2
#2Sachin Kumar Singh (LPU: Lovely Professional University)H-Index: 10
Last. Ankit Awasthi (LPU: Lovely Professional University)H-Index: 1
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Quercetin is reported to have numerous pharmacological actions, including antidiabetic, anti-inflammatory and anticancer activities. The main mechanism responsible for its pharmacological activities is its ability to quench reactive oxygen species (ROS) and, hence, decrease the oxidative stress responsible for the development of various diseases. Despite its proven therapeutic potential, the clinical use of quercetin remains limited because of its low aqueous solubility, bioavailability, and sub...
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#1Rajan Kumar (LPU: Lovely Professional University)H-Index: 1
#2Rubiya Khursheed (LPU: Lovely Professional University)H-Index: 2
Last. Ashish WadhwaniH-Index: 5
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Abstract Fisetin is a plant derived flavonoid that possesses anti-cancer, anti-oxidant and anti-Parkinson's activities. However, due to its lipophilicity it suffers from dissolution rate limited oral bioavailability that reduces its therapeutic efficacy. In order to overcome this issue self-nanoemulsifying drug delivery system (SNEDDS) of fisetin were formulated and characterized for droplet size, shape, zeta potential, cell viability, dissolution and permeability studies. Prepared SNEDDS (1.2 m...
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#1Rubiya Khursheed (LPU: Lovely Professional University)H-Index: 2
#2Sachin Kumar Singh (LPU: Lovely Professional University)H-Index: 10
Last. Kamal Dua (UTS: University of Technology, Sydney)H-Index: 13
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Abstract The growing disease burden of diabetes mellitus is an important public health concern, affecting over 400 million people globally. This epidemic, if not controlled in time, leads to life threatening complications, compromise in quality of life, and eventually mortality. Over time, many attempts have been made for the effective treatment of diabetes but true success has never been achieved. Pharmacological and non-pharmacological approaches for the treatment of hyperglycaemia have been e...
1 CitationsSource
#1Yogita Kumari (LPU: Lovely Professional University)H-Index: 4
#2Gurmandeep Kaur (LPU: Lovely Professional University)
Last. Omji Porwal (Ishik University)H-Index: 1
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Abstract In recent years, gold nanoparticles have emerged as unique non-invasive drug carriers for targeting drugs to their site of action. Their site specificity has helped in increasing drugs' efficacy at lower dose as well as reduction in their side effects. Moreover, their excellent optical properties and small size offer their utilization as diagnostic tools to diagnose tumors as well as other diseases. This review focuses on various approaches that have been used in last several years for ...
1 CitationsSource
#1Mayukh Banerjee (LPU: Lovely Professional University)H-Index: 1
#2Rubiya Khursheed (LPU: Lovely Professional University)H-Index: 2
Last. Narendra Kumar Pandey (LPU: Lovely Professional University)H-Index: 3
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#1Ankit AwasthiH-Index: 1
#2Rubiya KhursheedH-Index: 2
Last. Sachin Kumar SinghH-Index: 10
view all 4 authors...
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