Igor Nenadic
University of Marburg
PsychiatryDevelopmental psychologyPsychologyPsychosisClinical psychologySchizophrenia
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Publications 150
#1Nele StruckH-Index: 1
#2Axel KrugH-Index: 23
Last. Susanne MeinertH-Index: 8
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#1Adrian I. Campos (QIMR: QIMR Berghofer Medical Research Institute)H-Index: 1
#2Paul M. Thompson (SC: University of Southern California)H-Index: 141
Last. Robin BülowH-Index: 5
view all 63 authors...
Background: Suicidal behavior is highly heterogeneous and complex. A better understanding of its biological substrates and mechanisms could inform the design of more effective suicide prevention and intervention strategies. Neuroimaging studies of suicidality have so far been conducted in small samples, prone to biases and false-positive associations, yielding inconsistent results. The ENIGMA-MDD working group aims to address the issues of poor replicability and comparability by coordinating har...
#2Igor NenadicH-Index: 23
Last. Yann QuidéH-Index: 8
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#1Rachel M. Brouwer (UU: Utrecht University)H-Index: 32
#2Marieke Klein (UCSD: University of California, San Diego)
Last. Nitin Gogtay (APA: American Psychological Association)
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Human brain structure changes throughout our lives. Altered brain growth or rates of decline are implicated in a vast range of psychiatric, developmental, and neurodegenerative diseases. While heritable, specific loci in the genome that influence these rates are largely unknown. Here, we sought to find common genetic variants that affect rates of brain growth or atrophy, in the first genome-wide association analysis of longitudinal changes in brain morphology across the lifespan. Longitudinal ma...
#1Claas Flint (WWU: University of Münster)
#2Katharina Förster (WWU: University of Münster)H-Index: 8
Last. Axel Krug (University of Marburg)H-Index: 23
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Transgender individuals (TIs) show brain-structural alterations that differ from their biological sex as well as their perceived gender. To substantiate evidence that the brain structure of TIs differs from male and female, we use a combined multivariate and univariate approach. Gray matter segments resulting from voxel-based morphometry preprocessing of N = 1753 cisgender (CG) healthy participants were used to train (N = 1402) and validate (20% holdout N = 351) a support vector machine classify...
#1Eilis Hannon (University of Exeter)H-Index: 20
#2Emma Dempster (University of Exeter)H-Index: 27
Last. Marta Di Forta ('KCL': King's College London)
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Objective: Psychosis - a complex and heterogeneous neuropsychiatric condition characterized by hallucinations and delusions - is a common feature of schizophrenia. There is evidence for altered DNA methylation (DNAm) associated with schizophrenia in both brain and peripheral tissues. We aimed to undertake a systematic analysis of variable DNAm associated with psychosis, schizophrenia, and treatment-resistant schizophrenia, also exploring measures of biological ageing, smoking, and blood cell com...
Last. S. Fingas
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#1Simon SchmittH-Index: 1
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#1Maxim Zavorotnyy (University of Marburg)H-Index: 1
#2Rebecca Zöllner (University of Marburg)H-Index: 4
Last. Igor Nenadic (University of Marburg)H-Index: 23
view all 9 authors...
Abstract Background Intermittent theta-burst stimulation (iTBS), a novel repetitive transcranial magnetic stimulation (rTMS) technique, appears to have antidepressant effects when applied over left dorsolateral prefrontal cortex (DLPFC). However, its underlying neurobiological mechanisms are unclear. Proton magnetic resonance spectroscopy (1H-MRS) provides in vivo measurements of cerebral metabolites altered in major depressive disorder (MDD) like N-acetyl-aspartate (NAA) and choline-containing ...