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Junping Zheng
2Publications
Publications 2
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#1Junping Zheng (Hubei University of Chinese Medicine)
#2Jing Zhang (Hubei University of Chinese Medicine)
Last.Hongtao Liu (Hubei University of Chinese Medicine)
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Abstract Ethnopharmacological relevance Our previous research found that Sangguayin (SGY) deccoction made by four dietary and medicinal plant components (Leaf of Morus alba L., Root of Pueraria lobata (Willd.) Ohwi., Root of Dioscorea opposita Thunb. and Fruit of Momordica charantia L.) showed significant anti-diabetic effects on db/db mice and high fat diet induced obese mice. Nevertheless, it remained unclear what the role of gut microbiota in the hypoglycaemia effects of SGY. Aims of the stud...
#1Junping Zheng (Hubei University of Chinese Medicine)
#2Lin Zhu (Hubei University of Chinese Medicine)
Last.Hongtao Liu (Hubei University of Chinese Medicine)
view all 10 authors...
Abstract Non-alcoholic steatohepatitis (NASH) is associated with chronic inflammation and gut bacterial dysbiosis. Studies show that 1-deoxynojirimycin (DNJ) may improve NASH, yet the role of gut microbiota in protective effect of DNJ on NASH remains to be known. In present study, we aimed to examine how DNJ ameliorated high-fat diet (HFD)-induced mouse NASH through the regulation of gut microbiota dysbiosis. C57BL/6 J mice fed with HFD were treated with DNJ (0.1 mg/mL, in drinking water) for 4 ...
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