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Xinyi Liu
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#1Guanglei Li (Guangzhou Medical University)H-Index: 4
#2Xinyi Liu (JNU: Jinan University)
Last.Jianqiao Liu (Guangzhou Medical University)H-Index: 2
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Base editing systems show their power in modeling and correcting the pathogenic mutations of genetic diseases. Previous studies have already demonstrated the editing efficiency of BE3-mediated C-to-T conversion in human embryos. However, the precision and efficiency of a recently developed adenine base editor (ABE), which converts A-to-G editing in human embryos, remain to be addressed. Here we selected reported pathogenic mutations to characterize the ABE in human tripronuclear embryos. We foun...
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